Codon

JULY 27, 2023

There’s a TV show where a bunch of doctors are walking through a hospital corridor. Because it turns out that at least half of them , in humans, also bind to RNA molecules. How do transcription factors couple up with the correct RNA molecule? All the colors had the same brightness. From McKyton et al. in Current Biology.

Therapies 52

Therapies RNA DNA Engineering 52

Codon

JULY 27, 2023

There’s a TV show where a bunch of doctors are walking through a hospital corridor. Because it turns out that at least half of them , in humans, also bind to RNA molecules. How do transcription factors couple up with the correct RNA molecule? All the colors had the same brightness. From McKyton et al. in Current Biology.

Therapies 52

Therapies RNA DNA Engineering 52

Codon

DECEMBER 12, 2024

DNA and RNA molecules are also built from exclusively right-handed nucleic acids. Across the tree of life, organisms strictly require exactly one of the two chiral forms of their molecular building blocks — amino acids, nucleotides of RNA and DNA. 4 As far as we know, right-handed proteins never occur naturally.

DNA 104

DNA RNA Vaccine Virus 104

Codon

JANUARY 26, 2025

Even in good years, such as 2010-2011, the vaccine tops out at about 60 percent efficacy. RNA polymerase — the enzyme responsible for replicating influenza’s genetic material — lacks proofreading abilities, meaning that mutations aren’t corrected and can rapidly accumulate. Thomas Francis Jr.

Vaccine 101

Vaccine Immune Response Virus Clinical Trials 101

Codon

FEBRUARY 23, 2025

Countries supported by PEPFAR saw HIV cases drop by 52 percent in 2023 compared to 2010, outpacing the 39 percent global decline. Since zidovudine failed to interfere with DNA-to-DNA replication, Ostertag wondered if it could block RNA-to-DNA replication instead. This has happened before with other drugs.

Clinical Trials 70

Clinical Trials Virus Vaccine DNA 70