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How to Get Drugs Into the Brain

Drug Hunter

In 2010 , Pfizer developed a CNS-specific “MPO score” based on pK a , TPSA, and HBD count, but also lipophilicity measures of calculated partition coefficient (CLogP), calculated distribution coefficient (CLogD), and molecular weight (MW). 2010 , 1 (6), 435-449. ” ACS Chem. link] (Pfizer) Wager, T.T.; Verhoest, P.R.;

Drugs 206
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BioSpace Movers & Shakers, Nov. 20

The Pharma Data

He focused on corporate and business unit strategies, organizational transformations, product launches, growth strategies and new market entries. Prior to joining Bain in 2010, Retterath was a partner at Monitor Group and head of the New York office.