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Our data demonstrate that the CoREST complex is a critical mediator of the distinct melanoma phenotypes, working through the regulation of both the phenotype-defining genes MITF and AXL as well as the master regulators of epithelial-to-mesenchymal transitions (EMT) and phenotype switching in melanoma and other cancers, SNAIL/SLUG/ZEB1/ZEB2.
Prior to that, Mr Ho was at New Leaf Venture Partners, a leading healthcare venture capital firm, where he launched and managed the public investments and cross-over portfolio, and served as its Public Investment Director from 2010 to 2014. Regulation of cutaneous malignancy by gammadelta T cells. J Hemotother 5(5):503-9 (1996).
Even after a half-century of molecularbiology research, scientists didn’t know until recently how gas vesicles physically trap gas while occluding water. For more than a century, scientists thought of gas vesicles as little more than a natural curiosity and, later, as a way for microbes to regulate buoyancy.
.” Wellcome Collection , London I wrapped up my series on “30 Days of Great Biology Papers.” ” This was a series of tweets in which I told brief stories behind seminal papers, mostly in molecularbiology and biophysics. You can read all of them here. And it’s true, but only in an incomplete way.
.” Wellcome Collection , London I wrapped up my series on “30 Days of Great Biology Papers.” ” This was a series of tweets in which I told brief stories behind seminal papers, mostly in molecularbiology and biophysics. You can read all of them here. And it’s true, but only in an incomplete way.
Nature Reviews Genetics (2010). Journal of Theoretical Biology (2019). Link The second wave of synthetic biology: from modules to systems , by Purnick P.E.M. & Nature Reviews Molecular Cell Biology (2009). Link The second decade of synthetic biology: 2010–2020 , by Meng F. & Cell (2002).
Nature Reviews Genetics (2010). Journal of Theoretical Biology (2019). Link The second wave of synthetic biology: from modules to systems , by Purnick P.E.M. & Nature Reviews Molecular Cell Biology (2009). Link The second decade of synthetic biology: 2010–2020 , by Meng F. & PNAS (2013).
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