Codon

MAY 30, 2023

Read Programming inactive RNA-binding small molecules into bioactive degraders. Malaria deaths plummeted between 2010 and 2015, thanks mostly to the billions of dollars in philanthropic funding that were used to purchase bed nets and medicines. Molecular Therapy. Nature Communications. ACS Synthetic Biology. eClinicalMedicine.

DNA 52

DNA RNA Engineering Vaccine 52

Codon

MAY 30, 2023

Read Programming inactive RNA-binding small molecules into bioactive degraders. Malaria deaths plummeted between 2010 and 2015, thanks mostly to the billions of dollars in philanthropic funding that were used to purchase bed nets and medicines. Molecular Therapy. Nature Communications. ACS Synthetic Biology. eClinicalMedicine.

DNA 52

DNA RNA Engineering Vaccine 52

New Drug Approvals

SEPTEMBER 13, 2024

2] It first appeared in the scientific literature in 2010 or 2011. [16] “LY2456302 is a novel, potent, orally-bioavailable small molecule kappa-selective antagonist with activity in animal models predictive of efficacy in mood and addictive disorders” Neuropharmacology. 2] Aticaprant is taken by mouth. [1]

Treatment 62

Treatment Clinical Trials Pharmacokinetics Pharmaceuticals 62

Codon

DECEMBER 12, 2024

In 2010, researchers at the J. The most obvious defense would not be vaccines, but rather antibiotics; small molecules that treat or prevent bacterial infections. Making life from scratch is uncharted territory: this step alone could take a decade or more of troubleshooting. 14 But scientific efforts continue to bear fruit.

RNA 102

RNA DNA Vaccine Virus 102

New Drug Approvals

APRIL 18, 2023

H]Cl.NCCCCN(CC1=NC2=CC=CC=C2N1)[C@@H]3C4=NC=CC=C4CCC3 AMD-070 is a small molecule drug candidate that belongs to a new investigational class of anti-HIV drugs known as entry (fusion) inhibitors. 2010 Apr 22;53(8):3376-88. Molecular Weight 349.47 Appearance Solid Formula C 21 H 27 N 5 CAS No. 2309699-17-8 SMILES [H]Cl.[H]Cl.[H]Cl.NCCCCN(CC1=NC2=CC=CC=C2N1)[C@@H]3C4=NC=CC=C4CCC3

Clinical Trials 52

Clinical Trials Virus Small Molecule Trials 52

The Pharma Data

AUGUST 3, 2021

HLE BiTE ® molecules AMG 199 and AMG 910, targeting mucin 17 (MUC17) and claudin 18.2 AMG 176, a small molecule inhibitor of myeloid cell leukemia 1 (MCL-1), continues to enroll patients with hematologic malignancies. Tax Court to contest notices of deficiencies received from the IRS during the quarter for 2010, 2011 and 2012.

Biosimilars 52

Biosimilars Production Treatment FDA 52

Drug Target Review

NOVEMBER 1, 2024

Strategies for the synthesis and development of complex active pharmaceutical ingredients While the prevalence of biologics has grown within the pharmaceutical sector over recent decades, small molecules remain important and can offer significant advantages. References [1] Clemons et al.

Small Molecule 52

Small Molecule Production Pharmaceuticals Drug Development 52

Codon

FEBRUARY 16, 2025

Synthetic biologists have recently designed interacting protein clusters that act as neural networks inside living cells, gene circuits that can switch between OR and AND logic gates based on small molecule triggers , and even programmed a community of cells to execute a hashing function widely used in cryptography.

DNA 80

DNA RNA Engineering Small Molecule 80