biobide

SEPTEMBER 29, 2023

I n vivo trials being still an essential part of the preclinical research landscape, great efforts are been made to identify accurate NAM s that can be used in combination to reduce the use of animal testing.

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The Pharma Data

OCTOBER 25, 2020

26, 2020 /PRNewswire/ — Gmax Biopharm today announces that the first dose of GMA301 was given to the patient in its phase 1B trial to investigate the drug efficacy to treat pulmonary arterial hypertension (PAH). Phase 1A clinical trial in Australia was completed in 2020. HANGZHOU, China , Oct. www.gmaxbiopharm.com.

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New Drug Approvals

SEPTEMBER 6, 2024

1 , 2 It is also is under investigation in clinical trial NCT04269356 (Study to Assess the Way the Body Absorbs, Distributes, Breaks Down and Eliminates Radioactive BMS-986256 in Healthy Male Participants). 11:373-384 (2010)). 10:89-102 (2010)). Nature Immunol., Nature Rev.

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The Pharma Data

DECEMBER 14, 2020

15, 2020 /PRNewswire/ — Gmax Biopharm today holds ground-breaking ceremony for its Zhengzhou, China manufacturing site which is the production base for its GMA102 (T2D), GMA105 (obesity), and GMA301A/B (PAH for adult and children) drugs to be launched between 2023-2025, upon approval of respective clinical trials. HANGZHOU, China , Dec.

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Drug Target Review

SEPTEMBER 19, 2023

puts an end to the previous mandate that all drugs need to be tested on animals prior to human clinical trials. The first successful chip adaptation to a lung model was first described in 2010 by Donald Ingber, a bioengineer at Wyss institute. The US FDA Modernisation Act 2.0., Nature Cancer. 2022;3(4):418-36. Frontiers in Physiology.

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H1 Blog

JUNE 26, 2024

In a recent interview, Daniel Perez, the Director and Global Head of Health Equity for Worldwide Clinical Trials shared insights on health equity from personal and professional experiences. The experiences of his mother and aunt spurred bigger questions about how people become part of clinical trials.

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The Pharma Data

OCTOBER 14, 2020

Food and Drug Administration (FDA) to begin a Phase I clinical trial of hAd5-COVID-19, the company’s novel COVID-19 vaccine candidate that targets both the inner nucleocapsid (N), engineered to activate T cells, and outer spike (S) protein, engineered to activate antibodies against the coronavirus (SARS-CoV-2). i,ii,iii,iv.

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Drug Target Review

JUNE 19, 2024

That would provide wonderful information as we think about then going into a first-in-human clinical trial. MSTX), from 2010, and was also a member of its board of directors from 2011, until Mast’s merger with Savara, Inc. Do they affect the hearing capability of this species? SVRA) in April 2017.

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Therapies Small Molecule Pharmaceutical Companies Molecular Biology 84

Drug Target Review

NOVEMBER 1, 2023

The mission of the CCDD is to discover novel small-molecule therapeutics for the treatment of cancer and progress them to hypothesis testing phase 1 clinical trials. I work in the Centre for Cancer Drug Discovery (CCDD) at The Institute of Cancer Research in London, which is an academic drug discovery centre.

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Vial

MAY 1, 2024

The landscape of medical research is currently in the midst of an exciting transition wherein technology has rapidly become a critical tool for clinical trial management and patient data collection. in 2010 to 11.4% in 2010 to 11.4% in 2020 to enable continuous remote monitoring of real-world patient health data.

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The Pharma Data

JUNE 29, 2021

Susan previously led early-stage Oncology R&D, overseeing the successful progression of seven programmes into Phase III trials, with four new medicines now approved in countries around the world. Susan Galbraith joined AstraZeneca in 2010 and led the development of some of the Company’s most innovative cancer therapies.

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Crucial Data Solutions

APRIL 11, 2023

About Crucial Data Solutions Founded in 2010, Crucial Data Solutions (CDS) provides the most innovative data collection and clinical trial management technology on the market today. CDS’ drag-and-drop capabilities let you design anything and everything…this is going to be fun.”

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Clinical Trials Science Clinical Research Trials 40

The Pharma Data

MARCH 5, 2021

The FDA approval is based on data from the focuSSced trial, a Phase III randomised, double-blind, placebo-controlled clinical trial of 212 adults with systemic sclerosis. Supportive information was also used from the faSScinate trial, a Phase II/III, randomised, double-blind, placebo-controlled study in patients with SSc.

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The Pharma Data

DECEMBER 15, 2020

And during two testing periods — 2008/2010 and again in 2012/2014 — participants underwent repeated assessments (for an average of four years) designed to track changes in memory, language skills, concentration, attention, motor speed and mental “flexibility.”

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Clinical Trials Trials Research 52

The Pharma Data

MARCH 29, 2022

Following the completion of Phase 1 clinical trial for each immunology/inflammation target, Sanofi will be responsible for subsequent development activities, commercialization efforts, and related costs. IGM is eligible to receive tiered high single-digit to low-teen royalties on global net sales. About IGM Biosciences, Inc.

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Clinical Trials Engineering Licensing Licensing 52

The Pharma Data

JANUARY 11, 2021

MPH, Director of Cerebrovascular & Endovascular Neurosurgery at Semmes Murphey Neurologic & Spine Institute, Professor of Neurosurgery at the University of Tennessee , and Principal Investigator of the WEB-IT Pivotal Trial. For more information regarding the WEB Aneurysm Embolization System, please visit [link].

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Drug Target Review

SEPTEMBER 20, 2023

How AI/ML technology has accelerated drug discovery Although AI for drug discovery (AIDD) can be viewed as being in the initial phases of development and acceptance, compounds discovered using AIDD platforms are already entering clinical trials. Rob joined Cresset as CEO in 2010 and now also serves as Chairman of Cresset.

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Drug Target Review

FEBRUARY 28, 2024

Preclinical research on γδ T cells has made great strides since the cells were first identified in the 1980s, with γδ T-cell therapies from several companies, including IN8bio, now in or nearing clinical trials for various cancers. from 2003 to 2006, covering the biotechnology and life-science tools sectors.

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The Pharma Data

DECEMBER 30, 2020

Dodge’s team analyzed a nationwide database of close to 13,000 women who had stage 4 breast cancer between 2010 and 2015. Many of the trials were small, participants were not receiving chemotherapy or other systemic therapies and no information was available on the hormonal or HER2 status of the disease, she said.

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The Pharma Data

MAY 15, 2023

In a separate confirmatory arm of this phase III trial, the MenABCWY vaccine candidate showed immunological effectiveness against a panel of 110 diverse meningococcal serogroup B (MenB) invasive strains, which account for 95% of strains circulating in the US.

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PLOS: DNA Science

MAY 25, 2023

Father and daughter died within weeks of each other in early 2010. Interim results of the clinical trial, called MARINA, were presented at the American Academy of Neurology annual meeting in Boston in April, with final results of the phase 1/2 randomized, double-blind, placebo-controlled trial due in September.

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Treatment DNA RNA Clinical Trials 52

Codon

JUNE 18, 2024

Right) The passage of text from a 2010 review that inspired Mikhail Shapiro to engineer gas vesicles. Voigt, Biotechnology Journal (2010). In 2010, Shapiro picked up a review article and noticed two short paragraphs —included almost as an afterthought—about gas vesicles. 31,500x magnification. Walsby , 1994 & M.

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The Pharma Data

DECEMBER 14, 2020

Both vaccines have demonstrated about 94-95% efficacy in clinical trials. Since its founding in 2010, Moderna had raised more than $2.6 Most biotechs when they launch an IPO have no products in the clinic, or perhaps have one or two in early-stage trials. billion in equity financing.

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The Pharma Data

MARCH 30, 2021

The safety and effectiveness of the Jada System was evaluated in the PEARLE study, a prospective, single-arm, clinical trial, under an approved investigational device exemption from the U.S. Food and Drug Administration (FDA). Alydia Health was represented by Guggenheim Securities as financial advisor. About Alydia Health. and globally.

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Biosimilars Clinical Trials FDA Production 52

Drug Target Review

SEPTEMBER 26, 2023

Dr Rockley previously completed an MSc in Cancer Pharmacology and have experience in clinical research from an oncology clinical trial coordinator role. 2010 Aug;31(4):331–50. References Blinova K, Stohlman J, Vicente J, Chan D, Johannesen L, Hortigon-Vinagre MP, et al. Neurotoxicology. Drug Discov Today. 2009 Sep;14(17–18):876–84.

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The Pharma Data

NOVEMBER 22, 2021

Since 2005, AstraZeneca has achieved an nearlysix-fold enhancement in the proportion of its channel motes that have advanced from preclinical disquisition to completion of Phase III clinical trials – from 4 to 23. This enhancement moves AstraZeneca well above the current assiduity average success rate of 14 in the 2018-2020 timeframe.4.

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Molecular Biology Laboratories Engineering Hospitals 52

The Pharma Data

SEPTEMBER 1, 2020

Roche has an ongoing clinical trial program evaluating the role of Actemra©/RoActemra© (tocilizumab) in COVID-19 pneumonia. On 29 July we announced that the COVACTA trial did not meet its primary endpoint of improved clinical status in patients with COVID-19 associated pneumonia, or the key secondary endpoint of reduced patient mortality.

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The Pharma Data

MARCH 17, 2022

Since 2005, AstraZeneca has achieved an almost six-fold improvement in the proportion of its pipeline molecules that have advanced from preclinical investigation to completion of Phase III clinical trials – from 4% to 23%. Of the Company’s 80,000 employees, more than 13,000 work exclusively in R&D.

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Science Clinical Trials Disease Research 40

Precision for Medicine

JUNE 26, 2023

Precision applies a transformational approach to clinical research that integrates clinical trial design and execution with deep scientific knowledge, laboratory expertise, data sciences and advanced manufacturing solutions. This convergence is driving faster clinical development and approval. For more information, visit projectfarma.com.

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Science Small Molecule Clinical Research Engineering 40

Drug Target Review

APRIL 8, 2024

Identifying patients who are at high risk for relapse would likely help us isolate those high risk group of patients for more innovative clinical trials. He is the Principal Investigator for the NCI funded ALCHEMIST trial to study the role of erlotinib in patients with early-stage EGFR mutated lung cancer.

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The Pharma Data

NOVEMBER 15, 2020

In addition, Dr. Lee Babiss, a committed director since 2010, has announced his retirement and has stepped down from the board. This prestigious group of professionals will help lead the Company as it prepares for potential commercialization of its investigational cell therapy, MultiStem ®.

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Agency IQ

OCTOBER 20, 2023

FDA’s newest draft guidance lays out considerations for developing treatments for diabetic foot infections In a new draft guidance document released within weeks of a related clinical practice guideline, the FDA provides considerations for developing therapies to treat diabetic foot infections, focusing on Phase 3 efficacy trials.

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The Pharma Data

FEBRUARY 25, 2021

7 In clinical trials, the safety and immunogenicity of TicoVac was assessed across two age groups (1-15 years of age and 16-65 years of age). 2010 Jun 23;28(29):4558-65. “If approved in the U.S., The BLA is based on results from more than 40 years of experience and evidence outside the U.S. 2003 Dec 12;22(2):217-23. Heinz FX, et al.

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The Pharma Data

JANUARY 18, 2021

The forward-looking statements contained in this press release are also subject to risks not yet known to Biophytis or not currently considered material by Biophytis.

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The Pharma Data

JANUARY 11, 2021

Since 2010, IGM Biosciences has worked to overcome the manufacturing and protein engineering hurdles that have limited the therapeutic use of IgM antibodies. About IGM Biosciences, Inc.

Licensing 52

Licensing Licensing Therapies Engineering 52

New Drug Approvals

SEPTEMBER 13, 2024

2] As of July 2022, it is in phase 3 clinical trials for major depressive disorder. [2] hours following a single dose of 10 mg, which supported the 4 mg to 25 mg dosages that aticaprant is being explored at in clinical trials. [13] 2] It first appeared in the scientific literature in 2010 or 2011. [16] nM vs. 24.0 nM vs. 24.0

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The Strateos Blog: Drug Discovery

DECEMBER 5, 2022

 Digitization exploded for 60+ years 1940’s through 2010’s, but the idea really started 100 years earlier in 1843 when we conceptualized and created the first mechanical computer to store and process information. 10% more antibodies screened or 10% more clinical trials).

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