SCIENMAG: Medicine & Health

OCTOBER 31, 2023

AMES, Iowa – Since 2011, roughly 10,000 people in the U.S. Credit: Photo by Ryan Riley/Iowa State University AMES, Iowa – Since 2011, roughly […] have turned 65 every day. The Baby Boomer generation and those born before 1946 make up the country’s fastest growing age group, which is on track to outnumber children by 2035.

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Drug Discovery World

APRIL 11, 2024

Geneva: World Economic Forum, 2011 The post Positive results announced for COPD therapy appeared first on Drug Discovery World (DDW). As we plan our next clinical steps and follow-on studies, we are also exploring our partnering options to best enable us to bring our novel therapeutic approach to patients.”

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Therapies Clinical Trials Disease Trials 130

SCIENMAG: Medicine & Health

MARCH 22, 2024

There were multiple unsafe sleep practices at play in more than three-quarters of Sudden Unexpected Infant Deaths reported in 23 jurisdictions between 2011 and 2020, a new study reveals. The researchers say the findings underscore the need for more comprehensive safe-sleep education for new parents, including from healthcare providers.

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Research 72

Drug Discovery World

JULY 28, 2023

But new incentives are needed to help make it financially viable for pharmaceutical companies to advance new antibiotics through the later stages of clinical testing,” Professor Blaskovich said.

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Pharmaceutical Companies Pharmaceuticals Doctors Vaccine 243

SCIENMAG: Medicine & Health

JANUARY 24, 2024

The Fukushima Daiichi nuclear disaster, triggered by the earthquake and tsunami on March 11, 2011, resulted in a severe release of radioactive materials, including cesium, from the damaged nuclear reactors.

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Drug Discovery World

AUGUST 3, 2023

Founded in 2011, the company delivers discovery solutions across medicinal, synthetic, scale-up, process and computational chemistry, as well as DMPK, in vitro biology and in vivo pharmacology.

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Science Computational Chemistry Marketing Research 130

Antidote

JANUARY 29, 2024

Jamie received a diagnosis of stage IV melanoma in 2011, only 11 weeks after giving birth to her child. Not only will patients be able to gain access to potential new treatments, but they will also be directly contributing to research that can save lives — something that Jamie Troil Goldfarb has experienced firsthand.

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Clinical Trials Trials Doctors Treatment 122

Broad Institute

MARCH 8, 2024

Hung (2010 - 2011 awardee) James Bradner Jake Jaffe 2011 - 2012 Awardees Feng Zhang John Rinn Mitchell Guttman Anne Carpenter 2010 - 2011 Awardees Deborah T. Any questions about the Next Generation Awards program can be directed to Jacob Herman at jherman@broadinstitute.org. Hung Bradley Bernstein Tarjei Mikkelsen

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Research 52

Agency IQ

APRIL 12, 2024

BY RACHEL COE, MSC Late last year, the FDA published a draft update to its 2011 guidance on potency assays for cell and gene therapy products, unveiling a major shift in approach to the issue. Now, the deadline for feedback to that draft guidance has passed, and AgencyIQ has an analysis of the comments here.

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Production Laboratories FDA Regulations 59

Common Sense for Drug Policy Blog

DECEMBER 12, 2023

Total Adult Community Supervision Population in the US "From yearend 2011 to yearend 2021, the total adult community supervision population fell 22%, from 4,818,300 to 3,745,000 (table 1). Between 2011 and 2019, the U.S. Most of this decrease was due to a decline of 25% (1 million) in the number of adults on probation.

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Common Sense for Drug Policy Blog

JANUARY 5, 2024

This estimate is more than 5 times the most recent US estimate of ∼774,000 from 2011 [ 25 ]. Much of this increase is likely attributable to increases in IDU, but it is important to consider methodological differences in the creation of this 2018 estimate vs the 2011 estimate. during the past decade.

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Drugs Treatment Disease Therapies 40

SCIENMAG: Medicine & Health

JULY 5, 2023

But a study published by The BMJ today finds that less than half of approved first indications for new drugs in the US and Europe between 2011 and 2020 add substantial therapeutic value over existing treatments […]

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Treatment Drugs Disease 67

SCIENMAG: Medicine & Health

OCTOBER 11, 2023

However, the Great Atlantic Sargassum Belt (GASB) that emerged in 2011 has since then caused unprecedented inundations of this brown seaweed on Caribbean coastlines, with harmful effects on ecosystems while posing challenges […] 11, 2023) — Under normal conditions, the floating macroalgae Sargassum spp.

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SCIENMAG: Medicine & Health

SEPTEMBER 27, 2023

Credit: Copyright © 2011 Michael Bonert […] Over time, accumulating scarring distorts the liver, interferes with its blood supply and may progressively lead to worsening consequences, from cirrhosis to liver failure to liver cancer. In advanced cases, the only treatment is an organ transplant.

Treatment 52

Treatment 52

Covalent Modifiers

FEBRUARY 6, 2024

However, there has been a resurgence in covalent drug design following the success of several covalent drugs such as boceprevir (2011), ibrutinib (2013), neratinib (2017), dacomitinib (2018), zanubrutinib (2019), and many others.

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Drugs Research 65

FDA Law Blog: Biosimilars

MAY 27, 2024

Jennifer was with the firm from 2011-2017, before leaving for in-house roles at Apple, Abbott Laboratories, and Cognito Therapeutics. “Jennifer’s return adds depth and breadth to our device practice and her strong relationships from her earlier time at the firm has made for a seamless reentry,” said J.P. Ellison, Managing Director at HPM.

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Laboratories Compliance FDA Regulations 59

PLOS: DNA Science

MARCH 21, 2024

A Long and Winding Diagnostic Road The story begins in 2011, with Alessandra Biffi, MD, head of the clinical trial for MLD at the San Raffaele Telethon Institute for Gene Therapy in Milan. The boy was accepted into the clinical trial in Italy and received the gene therapy in 2011, but it was too late for Liviana.

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Therapies Clinical Trials DNA Trials 78

Common Sense for Drug Policy Blog

DECEMBER 15, 2023

Because of the very low levels of use of this drug by 2011, questions about its use were dropped from the questionnaires administered to 8th and 10th graders." This “club drug” was added to the survey in 2000. It showed little change in its usage levels through 2002. Since then use has declined in all grades. Johnston, L. Patrick, M.E.,

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Research Drugs 40

The Pharma Data

DECEMBER 7, 2020

older adults who reported owning and using hearing aids increased from 2011 to 2018, according to a research letter published online Dec. percent in 2011, 2015, and 2018, respectively. MONDAY, Dec. 7, 2020 — The proportion of U.S. 7 in JAMA Internal Medicine. Nicholas S. Reed, Au.D., percent).

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International Research 52

Broad Institute

FEBRUARY 15, 2024

Garber began serving as interim president of Harvard University on January 2, 2024, after having served as the provost and chief academic officer since 2011. Alan Garber By Rose Circeo February 15, 2024 Alan Garber Interim President, Harvard University Alan M.

Medical Schools 52

Medical Schools Science Government International 52

Agency IQ

APRIL 12, 2024

Draft guidance on potency assays for CGT products garners extensive stakeholder input Late last year, the FDA published a draft update to its 2011 guidance on potency assays for cell and gene therapy products, unveiling a major shift in approach to the issue. As a result, the 2011 guidance was generally seen as basic and outdated.

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Production FDA Therapies Biochemical Assays 40

New Drug Approvals

NOVEMBER 13, 2023

amcrasto@amcrasto /////////// Ref [1]. amcrasto@amcrasto /////////// Ref [1].

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Treatment Disease Therapies Production 62

National Drug & Alcohol Research Centre Blog

FEBRUARY 12, 2024

The study, published in Drug and Alcohol Review, examined deaths from acute alcohol poisoning in Australia, 2011–2022. A new study led by researchers at the National Drug and Alcohol Research Centre (NDARC), UNSW Sydney, has explored the circumstances of death and characteristics of fatal alcohol poisoning cases.

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Disease Treatment Research Drugs 110

Perficient: Drug Development

AUGUST 31, 2023

Kotlin is a programming language introduced by JetBrains in 2011. Our Kotlin tutorial includes. What is Kotlin? Pre-Requisites Features of Kotlin Kotlin Architecture What is Kotlin? Kotlin is free, has been free and will remain free. It is developed under the Apache 2.0 Google announced Kotlin is an official language for android development.

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Licensing Licensing International 105

Broad Institute

AUGUST 25, 2023

2011 In collaboration with MIT’s Picower Institute and McGovern Institute, the Stanley Center hosts its first two-day symposium , with the goal of bringing together leading scientists who work on the emerging genetics and biology of schizophrenia, bipolar disorder, autism, and other neurodevelopmental and psychiatric disorders.

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Research DNA International Disease 52

Drug Target Review

FEBRUARY 12, 2024

In 2007, I was involved in a ‘management buy-in’, before selling the company to Ipca Laboratories in 2011. I became a Director in 2005, responsible for the business’s continued growth from 7 initial founding members to 110 employees today.

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International Science Laboratories Pharmaceuticals 110

Common Sense for Drug Policy Blog

AUGUST 22, 2023

The risk environments framework provides a theoretical foundation for doing so ( Rhodes, 2002 ), emphasising the importance of enabling contexts and resources in advancing harm reduction ( Duff, 2009 , 2011 ). Substance use, including AAS, is influenced by various interacting factors within a social context.

Drugs 52

Drugs 52

Broad Institute

MARCH 14, 2024

In the new study, the researchers used a system called phage-assisted continuous evolution (PACE), first developed in Liu’s lab at Harvard in 2011, to generate a degron that might work with PT-179. PACE allows researchers to rapidly evolve new proteins that have useful features.

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Targeted Protein Degradation Small Molecule Medical Schools Science 141

PLOS: DNA Science

JUNE 27, 2024

The animals also tolerated conditions aboard the International Space Station in 2011, and seemed to have survived a crash into the moon from a probe in 2019. Some managed to lay eggs, but others succumbed eventually to the prolonged, intense UV exposure and lack of oxygen.

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DNA Vaccine International Research 64

Drug Target Review

NOVEMBER 27, 2023

a biopharmaceutical company, from August 2007 until its acquisition by Roche Holding AG in 2011. Previously, Dr Worland served as Chief Executive Officer of Anadys Pharmaceuticals, Inc., Prior to Anadys Pharmaceuticals, Inc., Dr Worland was Vice President and Head of Antiviral Research at Pfizer Inc. and Vice President at WarnerLambert Co.,

Molecular Biology 86

Molecular Biology Therapies Pharmaceuticals Treatment 86

The Pharma Data

NOVEMBER 17, 2020

31, 2011, to examine the impact of antibiotic exposure in the first two years of life. Zaira Aversa, M.D., from the Mayo Clinic in Rochester, Minnesota, and colleagues conducted a population-based cohort study involving children born in Olmsted County, Minnesota, between Jan. 1, 2003, and Dec.

Therapies 52

Therapies Doctors Disease Research 52

The Pharma Data

OCTOBER 21, 2020

Melike Yildirim, from the Georgia Institute of Technology in Atlanta, and colleagues used patient data from Medicaid Analytic eXtract files to identify patients with persistent asthma in 2010 and 2011 from New York and Michigan.

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Vaccine Government Research 52

The Pharma Data

JANUARY 12, 2021

The researchers found a significant decrease in the prevalence of albuminuria from 1988-1994 to 2011-2018 (38.9 Trends in albuminuria, reduced estimated glomerular filtration rate (eGFR), retinopathy, and self-reported cardiovascular disease were estimated.

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Disease Research 52

FDA Law Blog: Biosimilars

SEPTEMBER 11, 2023

In 2011, the Institute of Medicine released a report recommending elimination of the 510(k) process altogether ( link ), noting an inherent conflict between the legislative framework and FDA’s stated goals to protect patients and promote innovation in support of public health.

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Regulations FDA Marketing Science 64

The Pharma Data

APRIL 27, 2023

Results from the Phase 3 VALOR-HCM study evaluated CAMZYOS in patients with symptomatic obstructive HCM who met the 2011 ACC/AHA or 2014 ESC guideline criteria for septal reduction therapy (SRT) and who were referred for an invasive procedure.

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Therapies Treatment Trials Disease 40

New Drug Approvals

AUGUST 21, 2023

April 2011). Kaplan FS, Shore EM (April 2011). At Roche, palovarotene was evaluated in more than 800 individuals including healthy volunteers and patients with chronic obstructive pulmonary disease (COPD). [7] 22] Ipsen acquired Clementia in 2019. [23] 23] SYN Desjardins, C., Grogan, D. . 17 (4): 454–60. doi : 10.1038/nm.2334.

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FDA Clinical Trials Pharmaceuticals Treatment 52

The Pharma Data

MARCH 23, 2021

In the interview, Mr. Reinhardt was asked about the company’s $678 million settlement last year with the United States Government, which resolved claims that during the time period from 2002 to 2011, Novartis used certain promotional programs as a way improperly to induce doctors to prescribe Novartis products, in violation of US anti-kickback law.

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Doctors Government Production 52