Target-directed cancer: protein-ligand interactions
Drug Target Review
NOVEMBER 1, 2023
We can look at the detailed binding modes of our compounds bound to their protein targets in X-ray crystallography, and for drug targets or complexes that are difficult to crystallise we can use cryo-electron microscopy (cryoEM) as well. 2011) D67, 386-394) using PDB ID 4GV1 which was published as part of Addie et al. Acta Cryst.
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