Drug Discovery World

AUGUST 3, 2023

Founded in 2011, the company delivers discovery solutions across medicinal, synthetic, scale-up, process and computational chemistry, as well as DMPK, in vitro biology and in vivo pharmacology.

Science 130

Science Computational Chemistry Marketing Research 130

Sygnature Discovery

JULY 31, 2023

Founded in 2011, NuChem Sciences delivers expert integrated and standalone discovery solutions across medicinal, synthetic, scale-up, process and computational chemistry, as well as DMPK, in vitro biology and in vivo pharmacology.

Computational Chemistry 52

Computational Chemistry Science Pharmaceutical Companies Clinical Trials 52

Drug Target Review

NOVEMBER 1, 2023

For example, in the screening stage of a project we are trying to find initial starting points for optimisation by our medicinal and computational chemistry colleagues. 2011) D67, 386-394) using PDB ID 4GV1 which was published as part of Addie et al. Capivasertib (orange) bound to the kinase domain of AKT (blue). Acta Cryst.

Fragment Screening 96

Fragment Screening Biochemical Assays Small Molecule Biophysical Assays 96

LifeSciVC

APRIL 27, 2023

The premise at the time was that putting computational chemistry in the primary position for new molecule ideation would upend the drug discovery paradigm. set up a “virtual project team,” leverage Schrödinger scientists to lead computational chemistry, and do all the wet work at CROs. It did just that.

Small Molecule 52

Small Molecule Computational Chemistry Engineering Clinical Development 52