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This selectable marker enables the identification of cells which have taken up the GOIs and aids the initial selection of recombinant proteinexpressing cell lines. They work in the following way: the genes in an expression vector are flanked by inverted terminal repeat sequences (ITRs) to which a specific transposase enzyme can bind.
10 Reported cAMP as the second messenger signalling molecule conserved from bacteria to humans and modulates several biological processes, including proteinexpression, gene transcription, and cell development and differentiation. 2011): State of the Art in African Trypanosome Drug Discovery, Current topic of medical chemistry.
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