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Key considerations before commencing cell line development

Drug Target Review

A good introduction to the use of CHO cells for biotherapeutics production can be found in an article commemorating the 20th anniversary of the approval of a product produced using CHO cells. 2011), 108: 2141-2150 Schmieder V, Fieder J, et al. Host cell line, vector and cell line development process – to outsource or not?