Drug Target Review

NOVEMBER 27, 2023

Because these proteins have such a profound effect on cells, there is typically a second hurdle of regulation that needs to be overcome to make the proteins. eFFECTOR Therapeutics has developed a novel class of cancer drugs known as Selective Translation Regulator Inhibitors (STRIs), which directly target the eIF4F complex.

Molecular Biology 86

Molecular Biology Therapies Pharmaceuticals Treatment 86

Drug Target Review

OCTOBER 3, 2024

3 This change signals a major shift away from animal use in drug safety regulation and encourages the use of alternative methods like organ-on-chip or other animal-free technologies. Methods in Molecular Biology. Journal of Molecular Biology. 2011 Oct 1;413(1):261–78. 2021;291–306.

Molecular Biology 52

Molecular Biology Pharmacokinetics Laboratories Animal Testing 52

Codon

JUNE 25, 2024

Sometimes cells don’t take up the DNA, or unforeseen issues with the modified sequence arise—such as off-target mutations, unexpected protein modifications, or disruptions to gene regulation—that send us back to the drawing board. These setbacks can extend the timeline from days to weeks. coli growth. But it can improve.

DNA 70

DNA RNA Laboratories Engineering 70

Codon

JUNE 26, 2023

I pulled them from a 2011 blog post ( oH mY goD tHat’S nOt pEEr-ReVieWeD!!! ) Future Nobel Laureate, Paul Berg, narrated the video, which quickly became a cult classic moment in molecular biology history. plasmidsaurus @arjunrajlab (Regulation in biology is incredible. A protein rotates at 60 million RPM.

DNA 52

DNA Therapies Engineering Clinical Trials 52

Codon

JUNE 26, 2023

I pulled them from a 2011 blog post ( oH mY goD tHat’S nOt pEEr-ReVieWeD!!! ) Future Nobel Laureate, Paul Berg, narrated the video, which quickly became a cult classic moment in molecular biology history. plasmidsaurus @arjunrajlab (Regulation in biology is incredible. A protein rotates at 60 million RPM.

DNA 52

DNA Therapies Engineering Clinical Trials 52

Codon

AUGUST 10, 2023

Nature (2011). Link Gene Expression & Regulation →Genetic regulatory mechanisms in the synthesis of proteins , by Jacob F. & Journal of Molecular Biology (1961). Gene Expression and Regulation. Nature Reviews Molecular Cell Biology (2008). Link Molecular Cloning Techniques , by AddGene.

DNA 91

DNA Cell Biology Molecular Biology Engineering 91

Codon

AUGUST 10, 2023

Nature (2011). Link Gene Expression & Regulation →Genetic regulatory mechanisms in the synthesis of proteins , by Jacob F. & Journal of Molecular Biology (1961). Gene Expression and Regulation. Nature Reviews Molecular Cell Biology (2008). Link Molecular Cloning Techniques , by AddGene.

DNA 52

DNA Cell Biology Engineering Molecular Biology 52