Broad Institute

MAY 14, 2024

William Studier for development of widely used protein- and RNA-production platform By Corie Lok May 14, 2024 Breadcrumb Home Merkin Prize in Biomedical Technology awarded to F. Merkin Prize in Biomedical Technology for his development of an efficient, scalable method of producing RNA and proteins in the laboratory.

RNA 84

RNA Production Molecular Biology Laboratories 84

Drug Target Review

DECEMBER 7, 2023

Phage have been of interest to scientists as tools to understand fundamental molecular biology, as vectors of horizontal gene transfer and drivers of bacterial evolution, as sources of diagnostic and genetic tools, and as novel therapeutic agents. 2011 January 1 [2023 November 21]; 1(1):31-45. But what, exactly?” Bacteriophage.

RNA 59

RNA Immune Response DNA Molecular Biology 59

LifeSciVC

JULY 1, 2024

The central dogma of molecular biology is that information generally (with few exceptions) flows from DNA to RNA to Protein. In my own career, starting to write a blog was one of my most impactful “Friday afternoon experiments” – I even called it an experiment in my very first blogpost back in March 2011.

Science 80

Science Immune Response Molecular Biology RNA 80

Codon

JUNE 25, 2024

Proteins are colored blue and RNA molecules are colored orange and yellow. RNA and proteins comprise each ribosome, but the cell synthesizes these two biomolecules at different rates. In 2011, biophysicists at Stony Brook University estimated how the rates of protein folding impact E. The large and small ribosome subunits.

DNA 70

DNA RNA Laboratories Engineering 70

Codon

JUNE 26, 2023

I pulled them from a 2011 blog post ( oH mY goD tHat’S nOt pEEr-ReVieWeD!!! ) A T4 phage can hold 171,000 bases of DNA or other molecules, including proteins and RNA. It uses single-molecule RNA fluorescence to measure mRNAs and fluorescent reporters to measure the proteins. A protein rotates at 60 million RPM. in Nature.

DNA 52

DNA Therapies Engineering Clinical Trials 52

Codon

JUNE 26, 2023

I pulled them from a 2011 blog post ( oH mY goD tHat’S nOt pEEr-ReVieWeD!!! ) A T4 phage can hold 171,000 bases of DNA or other molecules, including proteins and RNA. It uses single-molecule RNA fluorescence to measure mRNAs and fluorescent reporters to measure the proteins. A protein rotates at 60 million RPM. in Nature.

DNA 52

DNA Therapies Engineering Clinical Trials 52

Codon

AUGUST 10, 2023

Nature (2011). Journal of Molecular Biology (1961). Link (Golden Gate assembly) Other Basic Methods & Cloning →Basic Methods in Cellular and Molecular Biology , by multiple authors. Link Molecular Cloning Techniques , by AddGene. Molecular Biology of the Cell, 4th Edition.

DNA 91

DNA Cell Biology Molecular Biology Engineering 91