Drug Target Review

NOVEMBER 1, 2023

We support the drug discovery projects of the CCDD with assay development and screening, biophysics, structural biology and recombinant protein production. With all these diverse methods we characterise protein-ligand interactions in many ways. 2011) D67, 386-394) using PDB ID 4GV1 which was published as part of Addie et al.

Fragment Screening 96

Fragment Screening Biochemical Assays Small Molecule Biophysical Assays 96

Broad Institute

MAY 14, 2024

I've always been interested in solving problems,” Studier told Brookhaven National Laboratory in a 2011 profile. When he launched his own lab at Brookhaven National Laboratory in 1964, Studier focused on sequencing the genes of the T7 bacteriophage and understanding the function of each of its corresponding proteins during infection of E.

RNA 84

RNA Production Molecular Biology Laboratories 84

Drug Target Review

JULY 5, 2023

5 And for the latter, the development of a technique to temporally track gene expression in CHO cells, which therefore has the potential to lead to the identification of targets to improve recombinant protein production. 2011), 108: 2141-2150 Schmieder V, Fieder J, et al. 2016), 32: 1301-1307 Matasci M, Baldo L, et al.

Engineering 105

Engineering DNA Laboratories Production 105

Agency IQ

APRIL 12, 2024

Draft guidance on potency assays for CGT products garners extensive stakeholder input Late last year, the FDA published a draft update to its 2011 guidance on potency assays for cell and gene therapy products, unveiling a major shift in approach to the issue.

Production 40

Production FDA Therapies Biochemical Assays 40

The Pharma Data

DECEMBER 3, 2020

Results demonstrated a substantial decrease in the time to diagnosis from >6 years of age (2011-2015) to <2 years of age (2019-2020). of all patients. About STK-001. STK-001 is an investigational new medicine for the treatment of Dravet syndrome currently being evaluated in a Phase 1/2a clinical trial.

Clinical Trials 52

Clinical Trials Protein Expression Pharmacokinetics Trials 52

Codon

AUGUST 10, 2023

Nature (2011). Link Gene Expression & Regulation →Genetic regulatory mechanisms in the synthesis of proteins , by Jacob F. & Link The PURE system for the cell-free synthesis of membrane proteins , by Kuruma Y. & Link The Elaboration of the Central Dogma. Scitable, by Nature Education. & Xie X.S.

DNA 91

DNA Cell Biology Molecular Biology Engineering 91

Codon

AUGUST 10, 2023

Nature (2011). Link Gene Expression & Regulation →Genetic regulatory mechanisms in the synthesis of proteins , by Jacob F. & Link The PURE system for the cell-free synthesis of membrane proteins , by Kuruma Y. & Link The Elaboration of the Central Dogma. Scitable, by Nature Education. & Xie X.S.

DNA 52

DNA Cell Biology Engineering Molecular Biology 52