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Target-directed cancer: protein-ligand interactions  

Drug Target Review

We often screen using a biochemical assay, but we can conduct cell-based screening as well. For fragment screening, we can screen with biophysical methods, such as thermal shift assays or, you may have heard about Surface Plasmon Resonance (SPR) which is a very sensitive biophysical technique used for fragment screening.

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Unique self-activating proteins for drug discovery

Drug Target Review

The need to identify new drug targets and candidate active pharmaceutical ingredients (APIs) for treating PAM is increasing, as the geographic range of N. 2012;Chapter 2:Unit2 8. Epub 2012/03/03. Recent reviews of N. fowleri exposure in the US is spreading to more northern climes due to climate change. Curr Protoc Pharmacol.