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Q&A: How Terra became a backbone of public health pathogen surveillance

Broad Institute

Credit: Jules Ko Photography 2012 Danny Park DP: Before Terra, only a handful of state public health labs were analyzing their own genomic data. BM: During COVID, there was an exponential increase in the need to analyze pathogen genomic data in public health settings quickly, locally, and often without deep bioinformatics capacity.

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Leveraging ADCs in precision oncology strategy

Drug Target Review

His research expertise focused on the use of genomics in translational oncology with a focus on clinical trials, genomically-informed drug combinations, liquid biopsy & MRD, and creating novel bioinformatic pipelines for cancer genome analyses.

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The Codon Guide to Synthetic Biology

Codon

PNAS (2012). . & Charpentier E. Philosophical Transactions of the Royal Society B (2016). Link A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity , by Jinek M. Link CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity , by Chen J.S. Science (2018).

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The Codon Guide to Synthetic Biology

Codon

PNAS (2012). Nature (2012). Nature (2012). . & Charpentier E. Philosophical Transactions of the Royal Society B (2016). Link A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity , by Jinek M. Science (2018). Link Nucleic acid detection with CRISPR-Cas13a/C2c2 , by Gootenberg J.S.

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