Obstacles and innovations of macrocyclic drug development
Drug Target Review
JANUARY 16, 2025
Food and Drug Administration (FDA) approved drugs, macrocycles are used to combat a range of diseases, including cancer, viral, fungal and bacterial infections, neurodegenerative and autoimmune diseases. Advanced Drug Delivery Reviews , 64:417, 2012. 5 Macrocycles as drugs Despite accounting for just four percent of the U.S.
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