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Marvin Caruthers receives inaugural Merkin Prize in ceremony at the Broad Institute for DNA synthesis technology

Broad Institute

Related links Merkin Prize Inaugural Merkin Prize in Biomedical Technology awarded to Dr. Marvin Caruthers for developing technology that efficiently synthesizes DNA The inaugural Richard N. Caruthers was announced as the winner in June for his development, in 1981, of an efficient, automated technology for synthesizing DNA.

DNA 52
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Day Zero Antivirals for Future Pandemics

Codon

Credit: OpenStax College The innate immune system has been evolutionarily successful for three reasons: its tools target the most fundamental properties of viruses , act as prophylactics —meaning they prevent diseases, rather than treat them—and are widespread. Other approaches could allow for less frequent dosing.

RNA 87
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CRISPR breakthroughs: New solutions for common diseases

Drug Discovery World

Rolf Turk , Senior Manager, Genomics Medicine at Integrated DNA Technologies, examines how CRISPR is being used to enhance cancer therapies. Years of development and fast-paced research have continued to unlock its potential, expanding how CRISPR can be used to treat, detect, and prevent common diseases such as cancer and Covid-19.

Disease 246
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TACACICLIB, AUR-102, AURIGENE

New Drug Approvals

The present invention is directed to methods of preparation of compound of formula (I) that is useful for inhibiting Cyclin-dependent kinase 7 (CDK7) and for treating diseases or disorders mediated thereby. May 30; 31(11): 2498-510, 2012). CDK7 also plays a role in transcription and possibly in DNA repair. Mar 23;25(6):839-50.

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A Molecular Portrait of ALS and FTD

Drug Target Review

Published on bit.bio’s website, this article authored by Dr Tony Oosterveen dives into the close relationship between FTD and ALS with a focus on mechanisms underlying the neuropathology of both diseases. ALS is the most common motor neuron disease and is estimated to affect more than 80,000 people worldwide.

RNA 98
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The Festival of Genomics and Biodata 2023 Comes to Boston

PLOS: DNA Science

In addition to rare genetic diseases, talks at the Festival will address Crohn’s disease, rheumatoid arthritis, polycystic ovarian syndrome, and neurological disease and cancers. See Socially Responsible Genetic Research with Descendants of the First Australians from 2012.) They shared the Nobel Prize in 2020.

DNA 52
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Gene-edited babies: Current techniques not safe, say experts

The Pharma Data

The technology could one day prevent parents from passing on heritable diseases to children, but the committee says much more research is needed. Most countries have regulations in place preventing babies being born after gene-editing, but the incident led to calls for strong international consensus.

DNA 52