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Marvin Caruthers receives inaugural Merkin Prize in ceremony at the Broad Institute for DNA synthesis technology

Broad Institute

Related links Merkin Prize Inaugural Merkin Prize in Biomedical Technology awarded to Dr. Marvin Caruthers for developing technology that efficiently synthesizes DNA The inaugural Richard N. Caruthers was announced as the winner in June for his development, in 1981, of an efficient, automated technology for synthesizing DNA.

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A Molecular Portrait of ALS and FTD

Drug Target Review

The specific proteins found in these aggregates can vary, but approximately 95 percent of ALS patients and 50 percent of FTD patients develop aggregates containing the TDP-43 protein (short for tar DNA binding protein 43). 14 TDP-43 is a DNA and RNA binding protein that regulates the expression and splicing of several target transcripts.

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Gene-edited babies: Current techniques not safe, say experts

The Pharma Data

Most countries have regulations in place preventing babies being born after gene-editing, but the incident led to calls for strong international consensus. One example of current technology is CRISPR, a biological system for altering DNA discovered in 2012. The scientist responsible was jailed, amid a fierce global backlash.

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Day Zero Antivirals for Future Pandemics

Codon

In 2012, a research group at MIT isolated the major components of mucus from pig stomachs (“porcine gastric mucins”) and tested its ability to inhibit infections caused by human papillomavirus, influenza virus, and Merkel cell polyomavirus. Other approaches could allow for less frequent dosing.

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The Festival of Genomics and Biodata 2023 Comes to Boston

PLOS: DNA Science

Two compelling talks will be “Long Noncoding RNAs as Key Regulators of Mood in Women,” from Orna Issler at the Neuroscience Institute at NYU Langone, and “Advising the US Congress and Policymakers on Issues Related to Pathogen Genomics, ” from Sarah Harvey, from the US Government Accountability Office. (See

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Meet the Flower Designer Who Built a Laboratory In His Home

Codon

Backyard astronomers discovered 42 new planets in 2012 , hobbyist paleontologists discovered the world’s largest dinosaur footprint near the Yorkshire coast in 2021, and Sebastian himself open-sourced protocols that make it easier for scientists to engineer plants. I use it to transform—or push DNA into—plant cells.

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Making Cells Young

Codon

Most cells (excluding T-cells and B cells after V(D)J recombination) in our body contain the same DNA but appear and behave in distinct ways: A neuron looks and acts very differently from a hepatocyte. While DNA is relatively stable , the epigenome is not; it has to orchestrate changes in cell state, cell type, and more.

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