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The science of ageing and restoring healthspan

Drug Target Review

We are at the forefront of drug development in an area of research called cellular rejuvenation, which is an approach that has the potential to address many diseases of ageing by restoring aged and injured cells to a more youthful and resilient state. The epigenome drifts with age, leading to dysregulated gene expression.

Science 145
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What Do Patients Have to Say about Gene Therapy Trials? An Upcoming FDA Public Meeting to Hear from Patients and Caregivers

FDA Law Blog: Drug Discovery

Bauer, Senior Regulatory Drug Expert & James E. Valentine — Incorporating patient and caregiver experiences into every phase of drug development has become increasingly prioritized during both development and review ( see, e.g. , previous coverage here ). By Larry J.

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Local HTTPS for Optimizely, IIS, and Kestrel using certificates (Pt 2)

Perficient: Drug Development

Prior to Windows Server 2012, there were a couple of challenges when it comes to hosting secure sites: SSL Scalability: In a multi-tenanted environment, such as a shared hosting, there is a limitation as to how many secure sites can be hosted on Windows Server, resulting in a low site-density.

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Obesity care gets personalised: tailoring therapies with Phenomix

Drug Target Review

Advancing drug development The implications of precision medicine in obesity care extend beyond selecting the right treatment for individual patients; it is also reshaping the development of next-generation obesity drugs. GenturaDxs technology is the basis of Luminexs acclaimed Aries platform.

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Introducing AMP: The Accelerating Medicines Partnership

NIH Director's Blog: Drug Development

It would seem like there’s never been a better time for drug development. Recent advances in genomics, proteomics, imaging, and other technologies have led to the discovery of more than a thousand risk factors for common diseases—biological changes that ought to hold promise as targets for drugs. Nat Rev Drug Discov.

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Unveiling the Power and Potential of GraphQL in Modern Web Development

Perficient: Drug Development

Understanding GraphQL: At its core, GraphQL is a query language and runtime for APIs that was developed by Facebook in 2012 and later open-sourced in 2015. In this comprehensive exploration, we’ll dive deep into the essence of GraphQL, its core principles, benefits, and real-world applications.

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Novartis’ CAR-T therapy Kymriah hits endpoint in follicular lymphoma trial

The Pharma Data

Kymriah was developed by Novartis in partnership with the University of Pennsylvania after the two parties signed a global collaboration deal for the therapy in 2012. “We