Drug Target Review

JUNE 12, 2023

Leveraging AI-guided structure-based drug design, Insilico’s research and development team generated an impressive portfolio of over 6,000 molecules and identified three highly promising hit series. He is an adjunct professor of artificial intelligence at the Buck Institute for Research on Aging.

Metabolic Stability 92

Metabolic Stability Clinical Trials Small Molecule Pharmacokinetics 92

Metabolite Tales Blog

MARCH 1, 2023

Bicyclic structures containing five membered rings such as indoles, consisting of a six-membered benzene ring fused to a five-membered pyrrole ring, are also increasingly relevant as growing research fields such as psychedelics make use of these scaffolds, often found in natural products. Table 1: Data from J.

Metabolic Stability 52

Metabolic Stability Drugs Pharmacokinetics Science 52

Drug Target Review

JANUARY 16, 2025

3 Antibodies are primarily used to target extracellular proteins, though researchers have generated antibodies that can reach intracellular targets. Metabolism was another concern in the early development of macrocyclic peptides. Ajay N Jain Ajay is VP of Research for the Optibrium s BioPharmics Division.

Drug Development 52

Drug Development Small Molecule Drugs FDA Approval 52