2012, Metabolic Stability and Small Molecule

Search:

DAY

WEEK

MONTH

YEAR

Select your country:
Sign up | Log in

2012

Metabolic Stability

Small Molecule

Game-changing pan-TEAD inhibitor for solid tumours

Drug Target Review

JUNE 12, 2023

The current version of Chemistry42 uses over 40 generative models, including generative autoencoders and generative adversarial networks as well as both structure-based and ligand-based drug design to generate and optimise de novo small molecules. The novel molecules were further ranked based on their ADME and selectivity profiles.

Metabolic Stability

Metabolic Stability Clinical Trials Small Molecule Pharmacokinetics

Obstacles and innovations of macrocyclic drug development

Drug Target Review

JANUARY 16, 2025

Traditionally, drug discovery has focused on small-molecule therapeutics, typically with a molecular weight of less than 500 Daltons. 2 Typically, small-molecule drugs target active sites buried inside proteins. What are macrocycles and why are they interesting for drug discovery?

Drug Development

Drug Development Small Molecule Drugs FDA Approval

Drug Discovery Digest

Game-changing pan-TEAD inhibitor for solid tumours

Obstacles and innovations of macrocyclic drug development

Stay Connected