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Target-directed cancer: protein-ligand interactions  

Drug Target Review

2013) 56, 2059-2073. What is different though, is that because we are an academic drug discovery centre, publication of our drug discovery research is integral to our mission. In addition, and in line with ICR’s strategy, part of our remit is to train the next generation of cancer drug discoverers. Acta Cryst.

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Obstacles and innovations of macrocyclic drug development

Drug Target Review

Considering the impact drug-like properties have on the chance of success. Drug Discovery Today , 18(13-14):659666, 2013. Journal of Medicinal Chemistry , 59(6):23122327, 2016. Yusof I, Segall MD. Bhardwaj G, OConnor J, Rettie S, et al. Accurate de novo design of membrane-traversing macrocycles. Cell , 185(19):35203532, 2022.