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Obstacles and innovations of macrocyclic drug development

Drug Target Review

Drug Discovery Today , 18(13-14):659666, 2013. Cyclic Peptide Design, Chapter 2: Strategies to Enhance Metabolic Stabilities. Journal of Medicinal Chemistry , 59(6):23122327, 2016. Yusof I, Segall MD. Considering the impact drug-like properties have on the chance of success. Bhardwaj G, OConnor J, Rettie S, et al.