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Target-directed cancer: protein-ligand interactions  

Drug Target Review

So that is a wide range of techniques to look at the protein-ligand interactions, all with the aim to guide the optimisation of our first screening hits to potent inhibitors that hopefully are cell-active at some point. 2013) 56, 2059-2073. Capivasertib (orange) bound to the kinase domain of AKT (blue). Acta Cryst.