Broad Institute

JANUARY 7, 2025

From her first biology course in high school, Rehm loved the logic of genetics: the clear trajectory from a simple code of DNA to RNA to proteins and how disrupting that process could lead to disease. NCBI then launched the ClinVar database in 2013 to house that information in a public archive.

Disease 121

Disease Science Laboratories Medical Schools 121

Codon

AUGUST 10, 2023

Journal of Molecular Biology (1961). Link (Golden Gate assembly) Other Basic Methods & Cloning →Basic Methods in Cellular and Molecular Biology , by multiple authors. PNAS (2013). Link Molecular Cloning Techniques , by AddGene. Molecular Biology of the Cell, 4th Edition.

DNA 98

DNA Cell Biology Molecular Biology Engineering 98

Codon

NOVEMBER 1, 2024

I’ve chosen these two because I think they are the linchpin by which we’ll be able to build broadly useful AI models for cell and molecular biology. Scientists are already building a model that can, for example, look at which RNA molecules are expressed in a cell at t=0 and predict how those molecules will change at t=1.

DNA 128

DNA RNA Molecular Biology Laboratories 128

Codon

AUGUST 10, 2023

Journal of Molecular Biology (1961). Nature Methods (2013). Link (Golden Gate assembly) Other Basic Methods & Cloning →Basic Methods in Cellular and Molecular Biology , by multiple authors. PNAS (2013). Link Molecular Cloning Techniques , by AddGene. Journal of Molecular Biology (2021).

DNA 52

DNA Cell Biology Engineering Molecular Biology 52