2013 Process Chemistry Trials 
Metabolite Tales Blog
JULY 5, 2023
Still, of the 34 macrocycles currently in clinical trials, only 18% are de novo designed. A multitude of macrocyclic antiviral drugs The antiviral drug simeprevir (TMC435) was approved for the treatment of chronic hepatitis C in 2013 but has since been discontinued in favour of more effective drugs. Balazs et al.,
Metabolite Tales Blog
JULY 5, 2023
Still, of the 34 macrocycles currently in clinical trials, only 18% are de novo designed. A multitude of macrocyclic antiviral drugs The antiviral drug simeprevir (TMC435) was approved for the treatment of chronic hepatitis C in 2013 but has since been discontinued in favour of more effective drugs. Balazs et al.,
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