Codon

FEBRUARY 28, 2023

Students learn the basics through words: DNA is transcribed to RNA, which is translated into proteins. How fast does DNA become RNA, or RNA protein? The other 30 percent is dominated by proteins first, followed by RNA and lipids. Let’s first think about DNA to RNA, or transcription. From Ron Milo (2013).

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RNA DNA Cell Biology Small Molecule 52

The Pharma Data

NOVEMBER 1, 2021

The project, detailed in an open-access paper in Computers in Biology and Medicine, incorporates models of three drug targets – main protease (Mpro), RNA-dependent RNA polymerase (RdRp) and Papain-like protease (PLpro) – for ensemble docking through DINC-COVID. DINC-COVID then scores the ligands’ success at binding.

Virus 52

Virus RNA Drugs Engineering 52

Codon

APRIL 19, 2023

In 2013, a Fusarium fungus — called Tropical Race 4 — was identified in Mozambique. In 2016, her team demonstrated that, by adding short snippets of DNA or RNA — which can target and “shut down” the MaMADS regulatory proteins — to bananas, it is possible to slow their ripening. From Elitzur T.

DNA 52

DNA RNA Engineering Regulations 52

Codon

APRIL 19, 2023

In 2013, a Fusarium fungus — called Tropical Race 4 — was identified in Mozambique. In 2016, her team demonstrated that, by adding short snippets of DNA or RNA — which can target and “shut down” the MaMADS regulatory proteins — to bananas, it is possible to slow their ripening. From Elitzur T.

DNA 52

DNA RNA Engineering Regulations 52

New Drug Approvals

SEPTEMBER 29, 2024

In addition, older dogs had bacterial antigens and ribosomal RNA in their brains, consistent with systemic infection seen in humans. 2013 Jan 1;36(4):665-77. Periodontitis has been linked epidemiologically to cognitive impairment, and P. gingivalis has been called a risk factor for Alzheimer’s disease ( Kanagasingam et al.,

Small Molecule 62

Small Molecule DNA Disease Trials 62

PLOS: DNA Science

MAY 16, 2024

” I’ve long thought that SARS-CoV-2, or an immediate viral predecessor, emerged years before 2019 – at least as far back as 2013. As soon as the initial RNA genome sequence of the pathogen that would be named SARS-CoV-2 was published, CDC and other organizations began developing diagnostic tests.

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Virus DNA RNA Vaccine 98

PLOS: DNA Science

MARCH 30, 2023

Comparing genome sequences is important because they provide a 4-letter language in the bases A, C, G, and T (for DNA) or A, C, G, and U (for RNA). The agency started tracking it in 2013, and the spread accelerated in 2015. For those who claim nothing’s being done to prevent future pandemics, please look at GISAID.

DNA 52

DNA Hospitals Laboratories Virus 52

Codon

DECEMBER 12, 2024

DNA and RNA molecules are also built from exclusively right-handed nucleic acids. Across the tree of life, organisms strictly require exactly one of the two chiral forms of their molecular building blocks — amino acids, nucleotides of RNA and DNA. 4 As far as we know, right-handed proteins never occur naturally.

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RNA DNA Vaccine Virus 104

Broad Institute

JANUARY 27, 2025

Generating data with the method is more than 10 times less expensive than comparable high-dimensional approaches such as high-throughput single-cell RNA sequencing and can be adapted to study a wide variety of cell types.

DNA 131

DNA RNA Science Research 131

Broad Institute

JANUARY 7, 2025

From her first biology course in high school, Rehm loved the logic of genetics: the clear trajectory from a simple code of DNA to RNA to proteins and how disrupting that process could lead to disease. NCBI then launched the ClinVar database in 2013 to house that information in a public archive.

Disease 121

Disease Science Laboratories Medical Schools 121

FDA Law Blog: Biosimilars

OCTOBER 24, 2024

In a landmark 2013 decision , a unanimous Supreme Court held that a naturally occurring DNA segment, even when isolated, is a product of nature and therefore does not meet the subject matter eligibility requirement for patentability. animal, viral, bacterial) DNA and RNA sequences. Supporters of AMP v.

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Laboratories DNA Testimonials Production 64

Codon

AUGUST 10, 2023

PNAS (2013). Link A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity , by Jinek M. Annual Review of Chemical and Biomolecular Engineering (2013). Link (Golden Gate assembly) Other Basic Methods & Cloning →Basic Methods in Cellular and Molecular Biology , by multiple authors.

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DNA Cell Biology Molecular Biology Engineering 98

Codon

NOVEMBER 1, 2024

Scientists are already building a model that can, for example, look at which RNA molecules are expressed in a cell at t=0 and predict how those molecules will change at t=1. SeqFISH, developed by Long Cai’s group at Caltech, maps the spatial positions of thousands of RNA, DNA, or protein molecules within single cells.

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DNA RNA Molecular Biology Laboratories 126

Codon

AUGUST 10, 2023

Nature Methods (2013). PNAS (2013). Link A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity , by Jinek M. Link In vitro integration of ribosomal RNA synthesis, ribosome assembly, and translation , by Jewett M.C. Molecular Systems Biology (2013). . & Reinberg D. Cell (2002).

DNA 52

DNA Cell Biology Engineering Molecular Biology 52

PLOS: DNA Science

FEBRUARY 29, 2024

I wrote this essay in 2013 , in response to common confusion of “embryo” and “fetus” – never imagining the blurring would extend to “baby” We scientists are sticklers for precision and accuracy. Various right-to-lifers in particular have trashed me, taking exception to my litany of biological facts.

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DNA Science Medical Schools RNA 97

Codon

FEBRUARY 23, 2025

.” In 1974, Wolfram Ostertag , a German geneticist at the Max Planck Institute, explored whether zidovudine could block retroviruses , which carry RNA, and use a reverse transcriptase enzyme to convert it into DNA before integrating into the host genome.

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Clinical Trials Virus Vaccine Trials 72