Science Daily: Pharmacology News

OCTOBER 23, 2024

A recovery program increased their population by 2010, but from 2014 to 2018, it fell to 30% of its peak due to a new acanthocephalan parasite, exacerbated by a prolonged drought. In the 1990s, the San Miguel Island fox nearly went extinct, with numbers dropping to just 15.

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Research 152

FDA Law Blog: Biosimilars

AUGUST 4, 2023

Because anabolic steroids are also abused to enhance athletic performance and increase muscle strength, Congress has enacted three laws regulating anabolic steroids: the Anabolic Steroid Control Acts of 1990 and 2004, and the Designer Anabolic Steroid Control Act of 2014 (“DASCA”). DASCA became law, amending the CSA, on December 18, 2014.

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Regulations Production Drugs Clinical Trials 52

Drugs.com

AUGUST 31, 2023

vasectomy rate increased by 26% between 2014 and 2021, THURSDAY, Aug. 31, 2023 -- Vasectomies are becoming more common in the United States, with rates surging by more than one-quarter during the past decade, a recent study reveals.

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Drugs.com

AUGUST 1, 2024

1, 2024 -- Celebrity suicides seem to be contagious, prompting everyday folks to consider the same, a new study suggests.The 2014 suicide death of comedian Robin Williams caused a thousand-fold increase in the risk of suicidal. THURSDAY, Aug.

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FDA Law Blog: Biosimilars

MARCH 18, 2025

In the generic filers view, the regulatory review period should have started in January 2014 when the patent was reissued rather than in April 2004, when the IND was opened, because the reissued patent did not exist in April 2004. The plain text of 35 U.S.C.

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Pharmaceutical Companies FDA Production Regulations 59

addgene Blog

NOVEMBER 2, 2023

In 2014, we wrote a blog post on CRISPR’s potential for correcting monogenetic diseases. There can be no doubt that CRISPR/Cas9 technology has been a breakthrough for the genome-editing field and the greater scientific community.

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Therapies Treatment Disease 127

addgene Blog

AUGUST 18, 2023

Viruses are simple – a genome packaged in a protein shell (Taylor, 2014). They’re so simple that we can’t even decide if they’re alive or not. Yet these simple, small particles have quite the outsized impact – and not just on the disease front.

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Virus Packaging Disease 92

Broad Institute

APRIL 25, 2024

By Allessandra DiCorato April 25, 2024 As night fell on July 20th, 2014, genomicist Christian Happi was at home with his family in Lagos, Nigeria when he received a phone call he would never forget. On October 20th, 2014, as Ebola continued to spread in Guinea and in neighboring Liberia and Sierra Leone, WHO declared Nigeria free of Ebola.

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Virus Hospitals Disease Government 132

SCIENMAG: Medicine & Health

AUGUST 15, 2023

By utilizing whole exome sequencing on tumor tissues and their non-tumor counterparts obtained from thirty SA-CRC patients diagnosed at Changzheng Hospital from 2014 to […]

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Research Treatment Hospitals Disease 92

Broad Institute

AUGUST 31, 2023

TBD By lcopelan@broadinstitute.org August 31, 2023 Yuhan Hao Neptune Bio Related Resources [link] MIA About Current Schedule Video Playlist Resources All talks Contact us MIA Talks Search - Any - Spring 2023 Fall 2022 Spring 2022 Fall 2021 Spring 2021 Fall 2020 Spring 2020 Fall 2019 Spring 2019 Fall 2018 Spring 2018 Fall 2017 Spring 2017 Fall 2016 (..)

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NIOSH Science Blog: Drugs

JUNE 7, 2023

Lack of safety and health training and language barriers are among the most frequently cited challenges companies face in promoting safety among immigrant workers (Flynn, 2014). Background The U.S. workforce is ethnically diverse. Unaddressed hearing loss is a serious and costly problem around the world.

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International 79

SCIENMAG: Medicine & Health

JULY 10, 2023

Based on its unique nature, Sharpless, Dong and coworkers introduced SuFEx as a new generation of click reaction in 2014 (Figure 1a). Organosulfur(VI) fluoride compounds display excellent chemical stability, and yet can efficiently realize diverse linkages via the activation of specific conditions.

Research 73

Research 73

Cytel

JANUARY 3, 2024

Ten years ago this month, in January 2014, the FDA issued the first version of its Technical Conformance Guide (by chance I also found comments provided by my friend Jozef Aerts already complaining about the use of SAS XPORT).

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Chemical Biology and Drug Design

NOVEMBER 13, 2023

WHO proclaimed the outbreak of the Ebola virus disease (EVD), in 2014 that killed hundreds of people in West Africa. Current figures show that the epidemic had reached 216 nations, where it had killed about 6,438,926 individuals and infected 590,405,710.

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Vaccine Laboratories RNA Clinical Development 100

SCIENMAG: Medicine & Health

JULY 18, 2023

Between 2002 and 2014, between 12% and 20% of UK adult smokers […]

Marketing 67

Marketing 67

LifeSciVC

DECEMBER 5, 2024

In 2014, we simplified further by focusing Atlas only on biotech. IPOs of currently-traded companies that went public between 2014-2024 have a median and average market cap today of $260M and $1.5B, where the top quartile is close to that average again as well. Top decile is $3B or so.

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Marketing RNA Science Drugs 76

Agency IQ

JULY 12, 2024

While the policy is similar in some respects to one first created by the FDA in 2014, the latest version is considerably more detailed regarding what it will – and won’t – allow companies to do.

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FDA Regulations Science Production 59

Common Sense for Drug Policy Blog

DECEMBER 20, 2023

Juvenile Drug Courts "As shown in Figure 13, a total of 420 JDCs were operating across the United States in 2014. Overall, between 2014 and 2021, the number of JDCs in the United States decreased by 30%." This number decreased to 305 by 2019 and again to 296 by the end of 2021.

Drugs 52

Drugs Treatment 52

Broad Institute

OCTOBER 3, 2024

Ultra-rare variants Since 2014, Epi25 has collected information from patients with multiple types of epilepsy, including a severe group of epilepsies known as developmental and epileptic encephalopathies as well as more common and milder forms called genetic generalized epilepsy and non-acquired focal epilepsy (NAFE).

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DNA Doctors Treatment Disease 133

Drug Target Review

JANUARY 8, 2024

acquired by Teva Pharmaceuticals in 2014. Before that, he served as president and CEO of AgeneBio, Inc., a clinical-stage private biopharma company developing therapies for neurological and psychiatric diseases. Earlier, he held the role of senior vice president & chief commercial officer at NuPathe Inc.,

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FDA Law Blog: Biosimilars

OCTOBER 24, 2023

Previous iterations of this guidance from 2009 and 2014 (blogged on here and here ) were known as Good Reprint Practices (GRP). The SIUU Guidance, which supersedes the 2014 Draft GRP Guidance, is not substantially different in that regard and contains similar information as to the types of disclosures previously recommended.

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FDA Clinical Trials Trials Government 64

Common Sense for Drug Policy Blog

OCTOBER 21, 2024

2014 ; Forrester, 2016 ), it was first described as a more prevalent additive in the unregulated drug supply of Puerto Rico ( Reyes et al., Xylazine in the Unregulated Drug Supply "Xylazine is a veterinary tranquilizer, which is not approved for human use in the United States, but is commonly used for sedating large animals ( Reyes et al.,

Drugs 52

Drugs 52

Crown Bioscience

JUNE 27, 2024

The phenomenal success of anti-PD-1 (programmed death-1) drugs for the treatment of cancer started in 2014 with the approvals of the monoclonal antibodies pembrolizumab (Keytruda) and nivolumab (Opdivo).

Drugs 52

Drugs Treatment Production 52

FDA Law Blog: Drug Discovery

JANUARY 30, 2025

For instance, the December 2024 guidance goes beyond the 2014 Expedited Programs for Serious Conditions Drugs and Biologics guidance (the last to deal substantively with accelerated approval) to describe FDAs expectation that sponsors take a proactive approach to ensuring confirmatory trials are completed within specified timelines.

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FDA Trials Disease Drugs 105

Cyclica

APRIL 28, 2023

That’s why, since 2014, Cyclica has provided University of Waterloo (UofW) students the opportunity to gain valuable work experience through a collaboration with the UofW’s’ co-op program. At Cyclica, we believe in giving back to the community and providing educational opportunities for the next generation.

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Broad Institute

OCTOBER 11, 2024

Large Language Models and Biological Foundation Models By lcopelan@broadinstitute.org October 11, 2024 Large Language Models and Biological Foundation Models Syed Rizvi Talks Search - Any - Fall 2024 Spring 2024 Fall 2023 Spring 2023 Fall 2022 Spring 2022 Fall 2021 Spring 2021 Fall 2020 Spring 2020 Fall 2019 Spring 2019 Fall 2018 Spring 2018 Fall 2017 (..)

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Broad Institute

AUGUST 30, 2024

Lightning Talks By lcopelan@broadinstitute.org August 30, 2024 Lightning Talks MIA About Current Schedule Video Playlist Resources All talks Contact us MIA Talks Search - Any - Fall 2024 Spring 2024 Fall 2023 Spring 2023 Fall 2022 Spring 2022 Fall 2021 Spring 2021 Fall 2020 Spring 2020 Fall 2019 Spring 2019 Fall 2018 Spring 2018 Fall 2017 Spring 2017 (..)

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Broad Institute

AUGUST 28, 2024

TBD By lcopelan@broadinstitute.org August 28, 2024 TBD Brian Cleary MIA About Current Schedule Video Playlist Resources All talks Contact us MIA Talks Search - Any - Fall 2024 Spring 2024 Fall 2023 Spring 2023 Fall 2022 Spring 2022 Fall 2021 Spring 2021 Fall 2020 Spring 2020 Fall 2019 Spring 2019 Fall 2018 Spring 2018 Fall 2017 Spring 2017 Fall 2016 (..)

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Broad Institute

AUGUST 22, 2024

TBD By lcopelan@broadinstitute.org August 22, 2024 TBD Abraham Gihawi MIA About Current Schedule Video Playlist Resources All talks Contact us MIA Talks Search - Any - Fall 2024 Spring 2024 Fall 2023 Spring 2023 Fall 2022 Spring 2022 Fall 2021 Spring 2021 Fall 2020 Spring 2020 Fall 2019 Spring 2019 Fall 2018 Spring 2018 Fall 2017 Spring 2017 Fall 2016 (..)

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Broad Institute

AUGUST 8, 2024

Microbiome By lcopelan@broadinstitute.org August 8, 2024 Microbiome Victoria Pascal MIA About Current Schedule Video Playlist Resources All talks Contact us MIA Talks Search - Any - Fall 2024 Spring 2024 Fall 2023 Spring 2023 Fall 2022 Spring 2022 Fall 2021 Spring 2021 Fall 2020 Spring 2020 Fall 2019 Spring 2019 Fall 2018 Spring 2018 Fall 2017 Spring (..)

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Broad Institute

AUGUST 8, 2024

Molecular dynamics By lcopelan@broadinstitute.org August 8, 2024 Molecular dynamics Ashkan Fakharzadeh Ghaan MIA About Current Schedule Video Playlist Resources All talks Contact us MIA Talks Search - Any - Fall 2024 Spring 2024 Fall 2023 Spring 2023 Fall 2022 Spring 2022 Fall 2021 Spring 2021 Fall 2020 Spring 2020 Fall 2019 Spring 2019 Fall 2018 Spring (..)

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Broad Institute

AUGUST 8, 2024

Tensor factorization + single-cell rna-seq By lcopelan@broadinstitute.org August 8, 2024 Tensor factorization + single-cell rna-seq Neriman Tokcan UMass Boston MIA About Current Schedule Video Playlist Resources All talks Contact us MIA Talks Search - Any - Fall 2024 Spring 2024 Fall 2023 Spring 2023 Fall 2022 Spring 2022 Fall 2021 Spring 2021 Fall (..)

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RNA 40

LifeSciVC

JANUARY 12, 2024

With a little over 50 new startups raising capital in 4Q24, we’re back to levels not seen for nearly a decade, at the start of the biotech secular bull market in 2013-2014.

Marketing 113

Marketing Science 113

Broad Institute

AUGUST 8, 2024

Single-cell genomics + LLM or OT By lcopelan@broadinstitute.org August 8, 2024 Single-cell genomics + LLM or OT David van Dijk Yale University MIA About Current Schedule Video Playlist Resources All talks Contact us MIA Talks Search - Any - Fall 2024 Spring 2024 Fall 2023 Spring 2023 Fall 2022 Spring 2022 Fall 2021 Spring 2021 Fall 2020 Spring 2020 (..)

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Broad Institute

SEPTEMBER 30, 2024

Talks Search - Any - Fall 2024 Spring 2024 Fall 2023 Spring 2023 Fall 2022 Spring 2022 Fall 2021 Spring 2021 Fall 2020 Spring 2020 Fall 2019 Spring 2019 Fall 2018 Spring 2018 Fall 2017 Spring 2017 Fall 2016 Spring 2016 Fall 2015 Summer 2015 Spring 2015 Spring 2014 Fall 2014

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The Pharma Data

JANUARY 12, 2021

For the four leading cancers, long-term declines in mortality have ceased for prostate cancer, slowed for breast and colorectal cancers, and accelerated for lung cancer, which accounted for almost 50 percent of the decrease in total mortality from 2014 to 2018. percent from 2014 to 2018 for men, from 1.8 to 5 percent overall.

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Treatment Research 52

Drug Target Review

OCTOBER 17, 2023

Waltham, MA: Academic Press, Imprint of Elsevier; 2014 [cited 2023 October 11] p.761-5. References 1 Krafts K, Ray SD, Yang N. Cell Proliferation. In: Wexler P. Encyclopaedia of Toxicology. Third Edition. link] 2 Adewale O, Ajiboye B, Emuowhochere R, et all. Biology of glucose metabolisation in cancer cells.

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Regulations Therapies Treatment Disease 98