Drug Target Review

NOVEMBER 17, 2023

Professor Alan Trounson AO CEO, Executive Director, Cartherics Alan is the past President of the Californian Institute for Regenerative Medicine (2007-2014), the Californian state’s $3 billion stem cell agency driving research in stem cell biology and facilitating the translation of stem cell discoveries into clinical therapies.

Therapies 118

Therapies Clinical Trials Cell Biology Trials 118

Broad Institute

OCTOBER 11, 2023

By Allessandra DiCorato October 11, 2023 In 2011, Robert Manguso was working in a cell biology lab when his mother was diagnosed with Merkel cell carcinoma, a rare and aggressive skin cancer. They are used to treat cancers including melanoma and non-small cell lung cancer, but work only for a small fraction of patients.

Research 137

Research Immune Response Clinical Trials Therapies 137

Drug Target Review

AUGUST 24, 2023

Prior to joining CatalYm, Christine co-founded Rigontec in 2014 where she led the company’s discovery and non-clinical development activities as Senior Vice President, Research. Shear forces induce ICAM-1 nanoclustering on endothelial cells that impact on T-cell migration. Current Opinion in Cell Biology.

Treatment 98

Treatment Therapies Clinical Development Cell Biology 98

PerkinElmer

JANUARY 21, 2022

1 To address the urgent need for new therapies, the UK’s Medical Research Council (MRC), a national public agency supporting health science and research, established the Dementias Platform United Kingdom (DPUK) in 2014. Unless something is done, experts predict these numbers will likely double within the next 20 years.

Cell Biology 52

Cell Biology Disease Treatment Science 52

Codon

JUNE 13, 2024

Credit: Oriane Hidalgo Per the book Cell Biology by the Numbers , each base pair of DNA occupies 1 nm 3 of space. 1 A single-celled protist, Polychaos dubia , was once thought to have the largest genome. So it was with some incredulity that I sat down, pulled out a scratch piece of paper, and jotted down some estimates.

DNA 62

DNA Molecular Biology Virus Cell Biology 62

Drug Target Review

MAY 21, 2024

I don’t think that it’s harder for women to enter careers in STEM, at least not in the scientific field—cell biology—that I have predominantly worked in. She returned to Cardiff in 2014 for a Research Fellowship at the European Cancer Stem Cell Research Institute.

Doctors 59

Doctors Science Research Cell Biology 59

NIH Director's Blog: Drug Discovery

APRIL 11, 2017

2014 Jan 9;8(1):e2628. [2] References : [1] Cofactor-independent phosphoglycerate mutase from nematodes has limited druggability, as revealed by two high-throughput screens. Crowther GJ, Booker ML, He M, Li T, Raverdy S, Novelli JF, He P, Dale NR, Fife AM, Barker RH Jr, Kramer ML, Van Voorhis WC, Carlow CK, Wang MW. PLoS Negl Trop Dis.

Small Molecule 52

Small Molecule Science Drug Development Disease 52