Broad Institute

OCTOBER 11, 2023

By Allessandra DiCorato October 11, 2023 In 2011, Robert Manguso was working in a cell biology lab when his mother was diagnosed with Merkel cell carcinoma, a rare and aggressive skin cancer. They are used to treat cancers including melanoma and non-small cell lung cancer, but work only for a small fraction of patients.

Research 137

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Drug Discovery World

OCTOBER 14, 2022

HTS as a tool for drug discovery has evolved rapidly since the origin of the technique in the 1990s. However, despite this long list of features that makes MALDI-TOF MS suitable for drug screening, it was not until 2014 that the first study detailing its use in a high-throughput assay was published. The future of HTS .

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DrugBank

JUNE 27, 2023

The general notion is that patients should be viewed individually, rather than strictly as members of some larger general population, and that their specific genetic background, environment, and lifestyle choices should be considered throughout drug development to the point of treatment and continuing patient care. Marcucio, R.

Disease 87

Disease Treatment Drugs International 87