DrugBank

JUNE 27, 2023

The general notion is that patients should be viewed individually, rather than strictly as members of some larger general population, and that their specific genetic background, environment, and lifestyle choices should be considered throughout drug development to the point of treatment and continuing patient care. Marcucio, R.

Disease 98

Disease Treatment Drugs Clinical Trials 98

Broad Institute

OCTOBER 11, 2023

By Allessandra DiCorato October 11, 2023 In 2011, Robert Manguso was working in a cell biology lab when his mother was diagnosed with Merkel cell carcinoma, a rare and aggressive skin cancer. They are used to treat cancers including melanoma and non-small cell lung cancer, but work only for a small fraction of patients.

Research 137

Research Immune Response Clinical Trials Therapies 137

NIH Director's Blog: Drug Discovery

APRIL 11, 2017

Before testing their peptides in animal models, they’ll continue to tinker with them in search of a version effective in disabling iPGM that might also make its way into cells more easily. Drug development is a notoriously long and arduous process, which too often ends in disappointment. 2014 Jan 9;8(1):e2628. [2]

Small Molecule 52

Small Molecule Science Drug Development Disease 52

Drug Target Review

JANUARY 16, 2025

She has a PhD in Microbiology and Cell Biology from the University of Illinois, followed by work in biochemistry as a post-doctoral fellow at UCSF. Nature Chemical Biology , 10(9):696698, 2014. Ajay N Jain Ajay is VP of Research for the Optibrium s BioPharmics Division. Biochemical Journal , 474(7):11091125, 2017.

Drug Development 52

Drug Development Small Molecule Drugs FDA Approval 52