Remove 2014 Remove Cell Biology Remove Regulations
article thumbnail

Cancer immunotherapy: GDF-15’s role in Anti-PD-1 resistance

Drug Target Review

Prior to joining CatalYm, Christine co-founded Rigontec in 2014 where she led the company’s discovery and non-clinical development activities as Senior Vice President, Research. Shear forces induce ICAM-1 nanoclustering on endothelial cells that impact on T-cell migration. Current Opinion in Cell Biology.

article thumbnail

Precision Medicine in the Genomic Era

DrugBank

14 As an unbiased method for genetic variant detection, GWAS holds the promise of identifying new genes and gene regulation mechanisms underlying a variety of conditions, including complex diseases. 10 , e1004724 (2014). Network expansion of genetic associations defines a pleiotropy map of human cell biology. PLoS Genet.

Disease 88
Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

article thumbnail

Neurobiology & Organismal Biology

Broad Institute

Our pilot study will span: 1) high-resolution EM (electron microscopy) of synaptic excitatory-inhibitory (E-I) balance and nearby glial cells; 2) functional electrophysiological signatures of altered E-I balance by sex in ACC brain slices; 3) molecular correlates of these impairments that can be targeted for recovery of function.

article thumbnail

The Codon Guide to Synthetic Biology

Codon

.” Foundations Basics of Synthetic Biology →Foundations for engineering biology , by Endy D. Link →A brief history of synthetic biology , by Cameron D.E. Nature Reviews Microbiology (2014). Link Synthetic biology: applications come of age , by Khalil A.S. & Journal of Molecular Biology (1961).

DNA 91
article thumbnail

The Codon Guide to Synthetic Biology

Codon

.” Foundations Basics of Synthetic Biology →Foundations for engineering biology , by Endy D. Link →A brief history of synthetic biology , by Cameron D.E. Nature Reviews Microbiology (2014). Link Synthetic biology: applications come of age , by Khalil A.S. & Journal of Molecular Biology (1961).

DNA 52