Drug Discovery World

JULY 23, 2024

3D genome folding DNA within the cell nucleus is more than the simple linear thread of primary sequence; it is tightly packed and folded non-randomly in a cell-type specific manner. Systematic localization of common disease-associated variation in regulatory DNA. Nature 2014:1-6. Science 2012;337(6099):1190-1195.

DNA 130

DNA Disease Regulations Molecular Biology 130

Codon

JUNE 25, 2024

However, they plod along as they clone plasmids—the loops of DNA that biologists use to manipulate and study organisms—because propagating them relies, in part, on the pace at which cells grow and divide. Most medicines, including insulin and semaglutide (the weight loss drug), are made using DNA cloning. However, E.

DNA 79

DNA RNA Laboratories Engineering 79

Codon

JULY 27, 2023

They’ve just finished sequencing the patient’s genome, but they don’t have “DNA sorting” software. billion units of DNA code are transcribed into more than a hundred volumes, each a thousand pages long, in type so small as to be barely legible.” You can read all of them here.

Therapies 52

Therapies RNA DNA Engineering 52

Codon

JULY 27, 2023

They’ve just finished sequencing the patient’s genome, but they don’t have “DNA sorting” software. billion units of DNA code are transcribed into more than a hundred volumes, each a thousand pages long, in type so small as to be barely legible.” You can read all of them here.

Therapies 52

Therapies RNA DNA Engineering 52

Codon

JUNE 18, 2024

Even after a half-century of molecular biology research, scientists didn’t know until recently how gas vesicles physically trap gas while occluding water. For more than a century, scientists thought of gas vesicles as little more than a natural curiosity and, later, as a way for microbes to regulate buoyancy. megaterium.

Engineering 70

Engineering Laboratories International Clinical Trials 70

Codon

AUGUST 10, 2023

.” Foundations Basics of Synthetic Biology →Foundations for engineering biology , by Endy D. Link →A brief history of synthetic biology , by Cameron D.E. Nature Reviews Microbiology (2014). Link Synthetic biology: applications come of age , by Khalil A.S. & PLoS Biology (2017).

DNA 97

DNA Cell Biology Molecular Biology Engineering 97

Codon

AUGUST 10, 2023

.” Foundations Basics of Synthetic Biology →Foundations for engineering biology , by Endy D. Link →A brief history of synthetic biology , by Cameron D.E. Nature Reviews Microbiology (2014). Link Synthetic biology: applications come of age , by Khalil A.S. & PLoS Biology (2017).

DNA 52

DNA Cell Biology Engineering Molecular Biology 52