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Gamma delta T cells: a rising star in cancer therapy

Drug Target Review

Prior to the founding of IN8bio, from 2014 to 2017, Mr Ho was the Founder and Managing Partner at AlephPoint Capital, a private healthcare investment fund. Regulation of cutaneous malignancy by gammadelta T cells. Mr Ho has worked in the biotechnology industry for almost 20 years. References Fichtner A, Ravens S, Prinz I.

Therapies 105
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Breaking the Speed Limit on Cell Division

Codon

Sometimes cells don’t take up the DNA, or unforeseen issues with the modified sequence arise—such as off-target mutations, unexpected protein modifications, or disruptions to gene regulation—that send us back to the drawing board. eLife (2014). These setbacks can extend the timeline from days to weeks.

DNA 82
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The Promise of Gas Vesicles

Codon

Even after a half-century of molecular biology research, scientists didn’t know until recently how gas vesicles physically trap gas while occluding water. For more than a century, scientists thought of gas vesicles as little more than a natural curiosity and, later, as a way for microbes to regulate buoyancy.

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Codon Digest: Seeing Colors After Gene Therapy

Codon

.” Wellcome Collection , London I wrapped up my series on “30 Days of Great Biology Papers.” ” This was a series of tweets in which I told brief stories behind seminal papers, mostly in molecular biology and biophysics. You can read all of them here. And it’s true, but only in an incomplete way.

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Codon Digest: Seeing Colors After Gene Therapy

Codon

.” Wellcome Collection , London I wrapped up my series on “30 Days of Great Biology Papers.” ” This was a series of tweets in which I told brief stories behind seminal papers, mostly in molecular biology and biophysics. You can read all of them here. And it’s true, but only in an incomplete way.

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Differentiated therapies: unlocking stem cell medicine with epigenetics

Drug Target Review

Any study of the genome is incomplete without considering the epigenomic framework within which genes are read and regulated. 2014 Jul 4;95102. Progress in molecular biology and translational science [Internet]. Charpentier E. Available from: [link] Ilyas M, Shah Q, Gul A, et al. 2024 Jan 1 [cited 2024 Oct 22];185209.

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The Codon Guide to Synthetic Biology

Codon

.” Foundations Basics of Synthetic Biology →Foundations for engineering biology , by Endy D. Link →A brief history of synthetic biology , by Cameron D.E. Nature Reviews Microbiology (2014). Link Synthetic biology: applications come of age , by Khalil A.S. & PLoS Biology (2017).

DNA 98