Drug Discovery World

OCTOBER 11, 2023

The main presentations will be followed by a panel discussion on how these new approaches – e.g., engineered proteins, antibodies, micro RNA, nanocarriers, antibody drug conjugates – can help address unmet need in oncology. He joined Taconic Biosciences in 2014 has been the Vice President of Commercial Products since 2017.

Research 130

Research Molecular Biology RNA Engineering 130

Drug Target Review

MAY 22, 2024

What are the key findings of Circio’s in vivo proof-of-concept for its circVec circular RNA platform technology compared to conventional mRNA-based expression with DNA vectors? Circular RNA (circRNA) has two major advantages versus mRNA in a vector-expression context.

Therapies 59

Therapies RNA Protein Expression DNA 59

Drug Discovery World

JANUARY 23, 2023

Base editing uses a guide RNA in partnership with a nickase version of Cas9, mutated to cut only a single strand of DNA, along with a deaminase enzyme to enable alteration of a single nucleotide 23,24. doi:10.1182/blood-2014-01-514752 8: Mandai M, Watanabe A, Kurimoto Y, et al. 1998;282:1145–1147. doi:10.1126/science.282.5391.1145.

Therapies 130

Therapies DNA Engineering RNA 130

Codon

JULY 27, 2023

.” Wellcome Collection , London I wrapped up my series on “30 Days of Great Biology Papers.” ” This was a series of tweets in which I told brief stories behind seminal papers, mostly in molecular biology and biophysics. How do transcription factors couple up with the correct RNA molecule?

Therapies 52

Therapies RNA DNA Engineering 52

Codon

JULY 27, 2023

.” Wellcome Collection , London I wrapped up my series on “30 Days of Great Biology Papers.” ” This was a series of tweets in which I told brief stories behind seminal papers, mostly in molecular biology and biophysics. How do transcription factors couple up with the correct RNA molecule?

Therapies 52

Therapies RNA DNA Engineering 52

Codon

JUNE 25, 2024

Proteins are colored blue and RNA molecules are colored orange and yellow. RNA and proteins comprise each ribosome, but the cell synthesizes these two biomolecules at different rates. A molecular model showing FtsZ proteins (in green and red), extracted from a microbe called Staphylococcus aureus , constricting a liposome (blue).

DNA 70

DNA RNA Laboratories Engineering 70

Codon

AUGUST 10, 2023

.” Foundations Basics of Synthetic Biology →Foundations for engineering biology , by Endy D. Link →A brief history of synthetic biology , by Cameron D.E. Nature Reviews Microbiology (2014). Link Synthetic biology: applications come of age , by Khalil A.S. & PLoS Biology (2017).

DNA 91

DNA Cell Biology Molecular Biology Engineering 91