Metabolism of macrocyclic drugs
Metabolite Tales Blog
JULY 5, 2023
[link] [4] Macrocyclization via Ring-Closing Metathesis in Drug Discovery & Process Chemistry. 20 (March 20, 2014). Drug Hunter article, June 2023. link] [5] European Medicines Agency (EMA), Committee for Medicinal Products for Human Use (CHMP), European Public Assessment Report (EPAR): Olysio (Simeprevir); p.20
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