Metabolism of macrocyclic drugs
Metabolite Tales Blog
JULY 5, 2023
A combination therapy of glecaprevir and pibrentasvir has recently been implicated in a case of liver injury. Figure 2 Human metabolism of glecaprevir Involvement of gut bacteria Grazoprevir (MK5172) is also used as part of combination therapy to treat chronic hepatitis C. 20 (March 20, 2014). Drug Hunter article, June 2023.
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