2014 Process Chemistry Trials 
Metabolite Tales Blog
JULY 5, 2023
Still, of the 34 macrocycles currently in clinical trials, only 18% are de novo designed. link] [4] Macrocyclization via Ring-Closing Metathesis in Drug Discovery & Process Chemistry. 20 (March 20, 2014). Several metabolites were observed with an S -oxide and an acyl glucuronide being major human metabolites.
Metabolite Tales Blog
JULY 5, 2023
Still, of the 34 macrocycles currently in clinical trials, only 18% are de novo designed. link] [4] Macrocyclization via Ring-Closing Metathesis in Drug Discovery & Process Chemistry. 20 (March 20, 2014). Several metabolites were observed with an S -oxide and an acyl glucuronide being major human metabolites.
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