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Precision Medicine in the Genomic Era

DrugBank

In contrast, non-coding mutations have effects on gene expression, transcript stability, and the physical state of the DNA itself (e.g., 14 As an unbiased method for genetic variant detection, GWAS holds the promise of identifying new genes and gene regulation mechanisms underlying a variety of conditions, including complex diseases.

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Making Eggs Without Ovaries

Codon

A meiotic cell nucleus beneath the microscope. The first reliable protocols to differentiate human iPSCs into PGC-like cells in vitro were published in 2015. During this process, the cells’ genomes ditch their methyl groups, an important epigenetic mark. The most important step seems to be erasing DNA methylation.

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The Codon Guide to Synthetic Biology

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Nature Reviews Molecular Cell Biology (2009). Link The second decade of synthetic biology: 2010–2020 , by Meng F. & Link Synthetic biology in mammalian cells: next generation research tools and therapeutics , by Lienert F. Nature Reviews Molecular Cell Biology (2014). . & Weiss R.

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The Codon Guide to Synthetic Biology

Codon

Nature Reviews Molecular Cell Biology (2009). Link The second decade of synthetic biology: 2010–2020 , by Meng F. & Link Synthetic biology in mammalian cells: next generation research tools and therapeutics , by Lienert F. Nature Reviews Molecular Cell Biology (2014). . & Weiss R.

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