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Discovering an Antimalarial Drug in Mao’s China

Codon

The existing literature written in English on this story tends to attribute Tu Youyou’s achievements to a solo discovery, an understandable consequence of Tu receiving the Nobel Prize in Physiology or Medicine in 2015. Department of Defense administered mefloquine, the synthetic drug developed at Walter Reed in the U.S.,

Drugs 141
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Precision Medicine in the Genomic Era

DrugBank

The general notion is that patients should be viewed individually, rather than strictly as members of some larger general population, and that their specific genetic background, environment, and lifestyle choices should be considered throughout drug development to the point of treatment and continuing patient care.  Jaccard, E.,

Disease 88
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Teaching immune cells how to kill

SugarCone Biotech

Learnings regarding immune geography and cell:cell contact are increasingly important as we consider how best to advance cell therapies for diverse hematologic malignancies and solid tumors ( www.aletabio.com ). This was an interesting finding and one that I think remains under-appreciated by the immuno-oncology drug development field.