Dark Matter Blog

APRIL 4, 2023

Prior to 2015, I had a casual relationship, at best, with targeting RNA. The bulk of my nearly three decades of experience up to that point was with drugging protein targets using a variety of modalities, but principally small molecules. Familiar tools to solve familiar problems with proteins. Welcome to the RNA world.

Small Molecule 52

Small Molecule RNA Fragment Screening DNA 52

BMG Labtech

FEBRUARY 24, 2025

Protein nitration assays are widely used in many research areas including but not limited to biochemistry , biotechnology , cell biology , microbiology , and molecular biology. In the highlighted study, the CLARIOstar Plus was used to detect peroxynitrite during phagocytosis with a small molecule sensor.

Small Molecule 52

Small Molecule Disease Licensing Licensing 52

Drug Target Review

MARCH 26, 2025

Likarda initially developed CSS to overcome the lack of effective delivery systems for cell therapies. It subsequently demonstrated promise for the administration of peptides, monoclonal antibodies and small molecules. Table 2 compares the characteristics of the microbead hormones with the other administration methods.

Therapies 52

Therapies Compliance Treatment Small Molecule 52