Drug Target Review

NOVEMBER 17, 2023

They recognise ‘cell stress molecules’ on the surface of infected, old, injured and cancerous cells without the need for complex pre-stimulation signals of the adaptive immune system (eg, T cells). NK cells can be readily extracted from umbilical cord blood or peripheral blood of adult donors.

Therapies 118

Therapies Clinical Trials Cell Biology Trials 118

Drug Target Review

APRIL 9, 2024

Initial works from the lab concentrated on exploring the role of replicative stress in cancer and ageing, for which the group combined cell biology, mouse models and drug development projects. Among other discoveries, the group developed inhibitors of the ATR kinase and showed their potential for cancer therapy.

RNA 64

RNA Cell Biology Clinical Development Disease 64

DrugBank

JUNE 27, 2023

Their use, as well as their integration into other types of data, has enabled the development of more precise therapies. whitehouse.gov [link] (2015). Nature 526 , 68–74 (2015). Network expansion of genetic associations defines a pleiotropy map of human cell biology.  Obama White House Archive.

Disease 98

Disease Treatment Drugs Clinical Trials 98

The Pharma Data

OCTOBER 22, 2020

INTERLINK-1 represents first Phase 3 study examining IO approach in R/M SCCHN patients who have been treatedwith a platinum-based therapy and PD-(L)1 inhibitor. Overall, the combination therapy data to date supports the expedited development of monalizumab and cetuximab in this indication. MARSEILLE, France, Oct.

Clinical Trials 40

Clinical Trials Trials Cell Biology Production 40

Codon

APRIL 9, 2024

The existing literature written in English on this story tends to attribute Tu Youyou’s achievements to a solo discovery, an understandable consequence of Tu receiving the Nobel Prize in Physiology or Medicine in 2015. Miller and Su published an article on Tu’s story in Cell in 2011. Nobody had an answer.

Drugs 138

Drugs Science Research Doctors 138

Codon

SEPTEMBER 22, 2024

A meiotic cell nucleus beneath the microscope. The first reliable protocols to differentiate human iPSCs into PGC-like cells in vitro were published in 2015. Reaching the oogonia stage marked an impressive achievement in germ cell biology, because previous methods only went up to the PGC stage.

DNA 109

DNA Laboratories Regulations Therapies 109

Codon

AUGUST 10, 2023

Nature Reviews Molecular Cell Biology (2009). Link The second decade of synthetic biology: 2010–2020 , by Meng F. & Link Synthetic biology in mammalian cells: next generation research tools and therapeutics , by Lienert F. Nature Reviews Molecular Cell Biology (2014). Nature (2015).

DNA 98

DNA Cell Biology Molecular Biology Engineering 98