NIH Director's Blog: Drug Development

JANUARY 5, 2016

But before diving into our first “new science” post of 2016, let’s take a quick look back at 2015 and some of its remarkable accomplishments. Four of 2015’s Top 10 featured developments directly benefited from NIH support—including Science’s “Breakthrough of the Year,” the CRISPR/Cas9 gene-editing technique. Protein Cell.

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Vaccine Science Engineering Disease 52

Drug Target Review

SEPTEMBER 4, 2023

I had earlier proposed the use of Palmatine and Silver Nitrate in the efficacy against the RNA structure of the COVID-19 virus. 2018): Silent Information Regulator 2 from Trypanosoma cruzi is a potential target to infection control, IntechOpen. We discovered it is highly effective and environmentally friendly. 12(11): e0006980.

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Drug Target Review

AUGUST 9, 2023

The specific proteins found in these aggregates can vary, but approximately 95 percent of ALS patients and 50 percent of FTD patients develop aggregates containing the TDP-43 protein (short for tar DNA binding protein 43). 14 TDP-43 is a DNA and RNA binding protein that regulates the expression and splicing of several target transcripts.

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RNA Regulations Disease DNA 98

Codon

SEPTEMBER 22, 2024

The first reliable protocols to differentiate human iPSCs into PGC-like cells in vitro were published in 2015. Erasing methyl groups on DNA is necessary for normal egg and sperm development. The most important step seems to be erasing DNA methylation. A meiotic cell nucleus beneath the microscope. Image provided by the author.

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Codon

AUGUST 10, 2023

Link Gene Expression & Regulation →Genetic regulatory mechanisms in the synthesis of proteins , by Jacob F. & Gene Expression and Regulation. Link Biological Networks & Mathematics →Network motifs in the transcriptional regulation network of Escherichia coli , by Shen-Orr S.S. FEMS Yeast Research (2015).

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DNA Cell Biology Molecular Biology Engineering 91

Codon

AUGUST 10, 2023

Link Gene Expression & Regulation →Genetic regulatory mechanisms in the synthesis of proteins , by Jacob F. & Gene Expression and Regulation. Link Biological Networks & Mathematics →Network motifs in the transcriptional regulation network of Escherichia coli , by Shen-Orr S.S. FEMS Yeast Research (2015).

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DNA Cell Biology Engineering Molecular Biology 52

Codon

APRIL 19, 2023

kilograms of CO 2 and 330 liters of water to make one kilogram of bananas, according to a 2015 study from Ecuador. This gene is regulated, in turn, by a small arsenal of other proteins from the MaMADS family. ( has a genome made of DNA. It takes 1.28 This gas is produced by an enzyme that is encoded by a gene, called MA-AC01.

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