2015 Metabolic Stability Treatment 
Drug Target Review
JUNE 12, 2023
With 13 preclinical candidates and three AI-designed drugs currently undergoing clinical trials, Insilico is spearheading a revolution in cancer treatment and beyond. Can you provide a summary of the key findings and implications of the preclinical studies on ISM6331 for the treatment of advanced solid tumours?
Metabolite Tales Blog
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This was surprising given that replacement of a phenyl with a pyrimidine and fluorination of aryl or heteroaryl rings are techniques often used to increase metabolic stability. ACS Medicinal Chemistry Letters 2015 6 (8), 925-929, [link] [11] Kinesin Spindle Protein (KSP) Inhibitors. Fan, Suzanne Tay, and Jae H. Christopher D.
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