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The role of STRIs in cancer

Drug Target Review

Because these proteins have such a profound effect on cells, there is typically a second hurdle of regulation that needs to be overcome to make the proteins. eFFECTOR Therapeutics has developed a novel class of cancer drugs known as Selective Translation Regulator Inhibitors (STRIs), which directly target the eIF4F complex.

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Chinese Government Arrests GenScript and Legend Biotech Founder for Smuggling

The Pharma Data

Zhang, who founded Legend Biotech in 2015 as a subsidiary of parent company GenScript, a company he also co-founded, had been under residential surveillance in connection with an investigation by the Customs Anti-Smuggling Department of Zhenjiang in China since Sept. Human genetic goods are tightly regulated by the Chinese government.

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A quiet revolution in the world of proteomics

DrugBaron

But data is accumulating to suggest it matters a lot: resolving one variant from another – and understanding what drives their relative concentrations – may be just as important in biology as regulation of gene expression. We are about to find out.

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The essential role of recombinant phage display antibody libraries

Drug Target Review

3 This change signals a major shift away from animal use in drug safety regulation and encourages the use of alternative methods like organ-on-chip or other animal-free technologies. 2015 May;521(7552):274–6. Methods in Molecular Biology. Journal of Molecular Biology. www.science.org. 2018;10(4):539–46.

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The Codon Guide to Synthetic Biology

Codon

Link Gene Expression & Regulation →Genetic regulatory mechanisms in the synthesis of proteins , by Jacob F. & Journal of Molecular Biology (1961). Gene Expression and Regulation. Nature Reviews Molecular Cell Biology (2008). Nature Reviews Molecular Cell Biology (2015).

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The Codon Guide to Synthetic Biology

Codon

Link Gene Expression & Regulation →Genetic regulatory mechanisms in the synthesis of proteins , by Jacob F. & Journal of Molecular Biology (1961). Gene Expression and Regulation. Nature Reviews Molecular Cell Biology (2008). Nature Reviews Molecular Cell Biology (2015).

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