Drug Target Review

NOVEMBER 27, 2023

Because these proteins have such a profound effect on cells, there is typically a second hurdle of regulation that needs to be overcome to make the proteins. eFFECTOR Therapeutics has developed a novel class of cancer drugs known as Selective Translation Regulator Inhibitors (STRIs), which directly target the eIF4F complex.

Molecular Biology 86

Molecular Biology Therapies Pharmaceuticals Treatment 86

Drug Discovery World

JULY 15, 2022

The first ‘final’ human genome sequence was announced some 20 years ago, and since then ‘next-generation’ sequencing technology and the human genome reference sequence have made it possible to sequence a whole genome within a week, providing widespread applications in both research and clinical medicine. Nature, 526, 75–81(2015).

DNA 130

DNA Disease Molecular Biology Science 130

DrugBaron

NOVEMBER 22, 2022

But data is accumulating to suggest it matters a lot: resolving one variant from another – and understanding what drives their relative concentrations – may be just as important in biology as regulation of gene expression. We are about to find out.

Bioinformatics 100

Bioinformatics Regulations Molecular Biology Engineering 100

Codon

AUGUST 10, 2023

Link The second decade of synthetic biology: 2010–2020 , by Meng F. & Link Synthetic biology in mammalian cells: next generation research tools and therapeutics , by Lienert F. Nature Reviews Molecular Cell Biology (2014). Journal of Molecular Biology (1961). Gene Expression and Regulation.

DNA 91

DNA Cell Biology Molecular Biology Engineering 91

Codon

AUGUST 10, 2023

Link The second decade of synthetic biology: 2010–2020 , by Meng F. & Link Synthetic biology in mammalian cells: next generation research tools and therapeutics , by Lienert F. Nature Reviews Molecular Cell Biology (2014). Journal of Molecular Biology (1961). Gene Expression and Regulation.

DNA 52

DNA Cell Biology Engineering Molecular Biology 52