Drug Discovery World

JANUARY 3, 2023

In the 13 years since it was first described, DNA-encoded library (DEL) technology has become a firmly established approach to small molecule hit generation in drug discovery. Targeted protein degradation and related modalities. Screening of DNA-Encoded Small Molecule Libraries inside a Living Cell.

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Drug Target Review

OCTOBER 4, 2023

The research community pressed on, turning to novel compounds that were substantially more potent than those used in the first generation. Groundbreaking strategies like proteolysis-targeting chimeric molecules (PROTACs) are also being explored. Dual cytotoxic payload ADCs could address the inherent heterogeneity in tumours.

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The Pharma Data

SEPTEMBER 15, 2020

We are happy to support their scientific efforts as they tackle complex research challenges that potentially address critical unmet medical needs for patients. Our Degradomer® class of targeted protein degraders expands on the Trilomer® concept, allowing highly specific degradation of disease-causing proteins.

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