Drug Target Review

NOVEMBER 1, 2023

2016 Jun 23;59(12):5604–21. Autotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid production. The Journal of Cell Biology. Structure–Activity Relationships of Small Molecule Autotaxin Inhibitors with a Discrete Binding Mode. 2016 Sep;7(1):11248.

Clinical Trials 134

Clinical Trials Trials Small Molecule Disease 134

The Pharma Data

OCTOBER 19, 2020

At Aduro, he was responsible for all manufacturing and supply chain activities for the company’s biologics and small molecules and managed a transatlantic team. USA) from the period of 2006 to 2016. in Cell Biology from Utrecht University. Kenilworth, N.J., Dr. van de Laar holds a M.Sc. About AM-Pharma.

Trials 40

Trials Small Molecule Cell Biology Clinical Trials 40

Elrig

APRIL 29, 2024

Fascinated by the potential of AI in medical research, I transitioned to BenevolentAI in early 2023 as a Biology Project Leader. There, I supported AI-enabled DD efforts in their small molecule portfolio. Driven by an interest in drug discovery Millie joined AstraZeneca after completion of her PhD at the end of 2020.

Bioinformatics 59

Bioinformatics Drugs Molecular Biology Cell Based Assays 59

Drug Target Review

JANUARY 16, 2025

Traditionally, drug discovery has focused on small-molecule therapeutics, typically with a molecular weight of less than 500 Daltons. 2 Typically, small-molecule drugs target active sites buried inside proteins. What are macrocycles and why are they interesting for drug discovery?

Drug Development 52

Drug Development Small Molecule Drugs FDA Approval 52

Drug Target Review

MARCH 26, 2025

Likarda initially developed CSS to overcome the lack of effective delivery systems for cell therapies. It subsequently demonstrated promise for the administration of peptides, monoclonal antibodies and small molecules. 2016 Dec;5(6):877-884. J Endocr Soc. 2020 Oct 30;5(1):bvaa161. doi: 10.1210/jendso/bvaa161. 7] Unger CA.

Therapies 52

Therapies Compliance Treatment Small Molecule 52