Broad Institute

APRIL 5, 2025

Base editing, which Lius team developed in 2016, is a gene editing technique that directly converts an individual DNA base pair into a different base pair. During his doctoral research at University of California Berkeley, Liu initiated the first general effort to expand the genetic code in living cells.

Science 139

Science Clinical Trials DNA Disease 139

Elrig

APRIL 29, 2024

Co-Chair: Millie Fox Co-Chair: Millie Fox Senior Drug Discovery Scientist, AstraZeneca Millie graduated from the University of Sussex with a Biochemistry degree in 2016, which included an industrial placement year at GSK, Stevenage.

Bioinformatics 59

Bioinformatics Drugs Molecular Biology Cell Based Assays 59

Codon

FEBRUARY 13, 2024

Some algorithms simply look for important similarities between phage and bacterial DNA sequences, a signal of the extensive gene-swapping that goes on when a particular virus and bacteria have shared history. Middle and Right) Once a bacteriophage lands on a cell, it injects its DNA through a tube (purple) into the unwilling host.

Therapies 130

Therapies Virus DNA Clinical Trials 130

Codon

JULY 27, 2023

There’s a TV show where a bunch of doctors are walking through a hospital corridor. They’ve just finished sequencing the patient’s genome, but they don’t have “DNA sorting” software. Transcription factors are proteins that bind to DNA and control gene expression. From McKyton et al.

Therapies 52

Therapies RNA DNA Engineering 52

Codon

JULY 27, 2023

There’s a TV show where a bunch of doctors are walking through a hospital corridor. They’ve just finished sequencing the patient’s genome, but they don’t have “DNA sorting” software. Transcription factors are proteins that bind to DNA and control gene expression. From McKyton et al.

Therapies 52

Therapies RNA DNA Engineering 52

Drug Target Review

DECEMBER 28, 2023

During the process of transformation from a normal cell into a cancer cell, a cell acquires a series of changes, or mutations, in its DNA. But DNA mutations can also result in changes to the proteins that are displayed on the surface of the cancer cell.

Bioinformatics 105

Bioinformatics Immune Response DNA Vaccine 105

Codon

JULY 21, 2024

A 2016 study found that rats who were tickled by their experimenters exhibited Freudensprünge, “joy jumps,” and emitted positive vocalizations. In 1959, before DNA sequencing, temperamentally-wild foxes used in the fur trade were bred for tameness. 9 Nor is breeding necessarily slow.

Research 120

Research Engineering Disease Science 120