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New molecular insights on medical cannabis

Drug Target Review

2,8-10 However, the number of compounds with satisfying pharmacokinetic parameters (PKD) are limited, with most unable to cross the blood-brain barrier or go sufficiently deep into a malignant tumour. He formerly worked at EMBL as a postdoctoral fellow from 2017 to 2020 where he discovered the inhibition of ATX with THC. 2018 Jun 13;5.

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Advanced 3D cell-based technologies

Drug Target Review

The organoid technology recreates different disease scenarios in addition to the healthy models with age specific phenotypes and enables recreating drug specific Pharmacokinetics that is more relevant to human in vivo system. From 3D cell culture to organs-on-chips. Trends in Cell Biology. 2010;328(5986):1662-8.